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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
40
Human Site:
Y656
Identified Species:
55
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
Y656
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
Y798
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
Y656
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Dog
Lupus familis
XP_531911
1031
117344
Y656
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
Y656
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Rat
Rattus norvegicus
Q62780
1032
117367
Y656
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
Y599
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Chicken
Gallus gallus
Q5F485
944
103035
T569
L
D
I
P
S
I
K
T
V
I
N
Y
D
V
A
Frog
Xenopus laevis
Q7ZY47
947
104061
D577
Y
D
V
A
R
D
I
D
T
H
T
H
R
I
G
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Y624
L
H
G
G
I
D
Q
Y
D
R
D
S
I
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
F794
L
H
G
G
I
D
Q
F
D
R
D
S
T
I
I
Honey Bee
Apis mellifera
XP_001122722
1018
114528
C640
L
H
G
G
I
D
Q
C
D
R
D
S
T
I
L
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
H589
L
H
G
G
I
D
Q
H
D
R
D
S
S
I
A
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
V519
M
G
L
R
A
V
C
V
Y
G
G
T
G
I
S
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
T756
L
H
G
A
K
D
Q
T
D
R
E
S
T
I
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
T813
L
H
G
G
K
D
Q
T
D
R
E
S
T
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
L832
D
D
L
L
R
E
L
L
R
R
G
Y
G
C
M
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
13.3
100
N.A.
80
80
80
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
26.6
13.3
100
N.A.
86.6
80
86.6
26.6
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
60
N.A.
N.A.
66.6
N.A.
6.6
P-Site Similarity:
73.3
N.A.
N.A.
80
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
6
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
6
6
0
0
0
0
0
6
0
% C
% Asp:
6
18
0
0
0
83
0
6
77
0
65
0
6
0
0
% D
% Glu:
0
0
0
0
0
6
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
6
77
71
0
0
0
0
0
6
12
0
12
0
6
% G
% His:
0
77
0
0
0
0
0
6
0
6
0
6
0
0
0
% H
% Ile:
0
0
6
0
65
6
6
0
0
6
0
0
48
89
6
% I
% Lys:
0
0
0
0
12
0
6
0
0
0
0
0
0
0
0
% K
% Leu:
83
0
12
6
0
0
6
6
0
0
0
0
0
0
6
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
48
% N
% Pro:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
6
12
0
0
0
6
83
0
0
6
0
0
% R
% Ser:
0
0
0
0
6
0
0
0
0
0
0
77
6
0
18
% S
% Thr:
0
0
0
0
0
0
0
18
6
0
6
6
24
0
0
% T
% Val:
0
0
6
0
0
6
0
6
6
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
48
6
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _