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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
43.03
Human Site:
Y972
Identified Species:
59.17
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
Y972
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
Y1114
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
Y972
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Dog
Lupus familis
XP_531911
1031
117344
Y972
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
Y973
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Rat
Rattus norvegicus
Q62780
1032
117367
Y973
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
Y915
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Chicken
Gallus gallus
Q5F485
944
103035
H874
Y
R
H
G
E
G
R
H
G
D
S
H
R
H
A
Frog
Xenopus laevis
Q7ZY47
947
104061
S884
G
G
E
G
R
R
E
S
S
R
D
G
E
G
R
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Y959
A
I
T
I
R
G
T
Y
F
P
P
G
K
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
Y1165
G
L
T
V
R
G
T
Y
V
P
Q
G
K
N
P
Honey Bee
Apis mellifera
XP_001122722
1018
114528
Y958
G
L
T
V
R
G
T
Y
I
A
P
G
K
A
P
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
H911
G
I
S
V
R
G
V
H
V
P
P
G
K
E
P
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
G811
K
E
V
T
K
N
S
G
F
S
G
K
G
F
K
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
F1053
A
I
T
T
R
G
Q
F
F
P
P
G
K
V
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
F1107
A
I
T
T
R
G
Q
F
Y
P
T
G
R
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
Y1133
S
I
T
T
K
G
N
Y
Y
A
P
G
K
E
P
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
13.3
100
N.A.
60
60
60
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
20
100
N.A.
73.3
73.3
80
20
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
73.3
N.A.
N.A.
53.3
N.A.
60
P-Site Similarity:
80
N.A.
N.A.
73.3
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
0
0
0
0
12
0
0
0
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
6
6
0
0
0
0
% D
% Glu:
0
6
6
0
6
0
6
0
0
0
0
0
6
59
0
% E
% Phe:
0
0
0
0
0
0
0
12
59
0
0
0
0
6
0
% F
% Gly:
24
6
0
12
0
89
0
6
6
0
6
89
6
6
0
% G
% His:
0
0
6
0
0
0
0
12
0
0
0
6
0
6
0
% H
% Ile:
0
71
0
48
0
0
0
0
6
0
0
0
0
6
0
% I
% Lys:
6
0
0
0
12
0
0
0
0
0
0
6
77
0
6
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
6
6
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
71
71
0
0
0
83
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
6
0
0
0
0
% Q
% Arg:
0
6
0
0
83
6
6
0
0
6
0
0
12
0
6
% R
% Ser:
6
0
6
0
0
0
6
6
6
6
6
0
0
0
0
% S
% Thr:
0
0
77
24
0
0
59
0
0
0
6
0
0
0
0
% T
% Val:
0
0
6
18
0
0
6
0
12
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
65
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _