Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 43.03
Human Site: Y972 Identified Species: 59.17
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 Y972 A I T I R G T Y F P P G K E P
Chimpanzee Pan troglodytes XP_517939 1173 133261 Y1114 A I T I R G T Y F P P G K E P
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 Y972 A I T I R G T Y F P P G K E P
Dog Lupus familis XP_531911 1031 117344 Y972 A I T I R G T Y F P P G K E P
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 Y973 A I T I R G T Y F P P G K E P
Rat Rattus norvegicus Q62780 1032 117367 Y973 A I T I R G T Y F P P G K E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 Y915 A I T I R G T Y F P P G K E P
Chicken Gallus gallus Q5F485 944 103035 H874 Y R H G E G R H G D S H R H A
Frog Xenopus laevis Q7ZY47 947 104061 S884 G G E G R R E S S R D G E G R
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 Y959 A I T I R G T Y F P P G K E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 Y1165 G L T V R G T Y V P Q G K N P
Honey Bee Apis mellifera XP_001122722 1018 114528 Y958 G L T V R G T Y I A P G K A P
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 H911 G I S V R G V H V P P G K E P
Sea Urchin Strong. purpuratus XP_784902 869 99209 G811 K E V T K N S G F S G K G F K
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 F1053 A I T T R G Q F F P P G K V P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 F1107 A I T T R G Q F Y P T G R I P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 Y1133 S I T T K G N Y Y A P G K E P
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 13.3 100 N.A. 60 60 60 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 20 100 N.A. 73.3 73.3 80 20
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 73.3 N.A. N.A. 53.3 N.A. 60
P-Site Similarity: 80 N.A. N.A. 73.3 N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 0 0 0 0 0 0 0 0 12 0 0 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 6 6 0 0 0 0 % D
% Glu: 0 6 6 0 6 0 6 0 0 0 0 0 6 59 0 % E
% Phe: 0 0 0 0 0 0 0 12 59 0 0 0 0 6 0 % F
% Gly: 24 6 0 12 0 89 0 6 6 0 6 89 6 6 0 % G
% His: 0 0 6 0 0 0 0 12 0 0 0 6 0 6 0 % H
% Ile: 0 71 0 48 0 0 0 0 6 0 0 0 0 6 0 % I
% Lys: 6 0 0 0 12 0 0 0 0 0 0 6 77 0 6 % K
% Leu: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 6 6 0 0 0 0 0 0 6 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 71 71 0 0 0 83 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 6 0 0 0 0 % Q
% Arg: 0 6 0 0 83 6 6 0 0 6 0 0 12 0 6 % R
% Ser: 6 0 6 0 0 0 6 6 6 6 6 0 0 0 0 % S
% Thr: 0 0 77 24 0 0 59 0 0 0 6 0 0 0 0 % T
% Val: 0 0 6 18 0 0 6 0 12 0 0 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 0 0 65 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _