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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHOU All Species: 22.12
Human Site: S237 Identified Species: 32.44
UniProt: Q7L0Q8 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L0Q8 NP_067028.1 258 28218 S237 Q Q P K K S K S R T P D K M K
Chimpanzee Pan troglodytes XP_525089 191 21622 S170 Q Q P K K S K S R T P D K M K
Rhesus Macaque Macaca mulatta XP_001083463 258 28214 S237 Q Q P K K S K S R T P D K M K
Dog Lupus familis XP_536354 258 28130 S237 Q Q P K K S K S R T P D K M K
Cat Felis silvestris
Mouse Mus musculus Q9EQT3 261 28335 S240 L Q P K K S K S R T P D K V R
Rat Rattus norvegicus Q9Z1Y0 236 26147 K215 H K A R L E K K L N A K G V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521402 305 33267 S284 Q P P K K A K S R T P D K M K
Chicken Gallus gallus Q90694 191 21254 D170 K G L K N V F D E A I L A A L
Frog Xenopus laevis NP_001087939 243 26985 A223 G Q R E R K M A A T A N K M K
Zebra Danio Brachydanio rerio NP_001007444 254 28260 K233 Q Q Q K R L K K R T P D K M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40793 191 21384 D170 K G L K N V F D E A I L A A L
Honey Bee Apis mellifera XP_395770 272 29950 R252 A S L L C R R R K P L S L W R
Nematode Worm Caenorhab. elegans Q05062 191 21147 D170 K G L K N V F D E A I L A A L
Sea Urchin Strong. purpuratus XP_787983 288 32045 K266 E K I P P P P K R A Q D T K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38912 198 21710 F170 Q Q N V K A V F D A A I K V V
Baker's Yeast Sacchar. cerevisiae P19073 191 21304 F169 Q R G L K N V F D E A I V A A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.8 99.6 98 N.A. 90.8 55 N.A. 54.7 44.9 60.8 71.7 N.A. 44.9 43.7 44.9 51
Protein Similarity: 100 68.5 100 98.8 N.A. 93.8 72 N.A. 64.5 58.1 75.5 80.6 N.A. 57.7 62.1 57.3 63.5
P-Site Identity: 100 100 100 100 N.A. 80 6.6 N.A. 86.6 6.6 33.3 66.6 N.A. 6.6 0 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 33.3 N.A. 93.3 13.3 60 80 N.A. 13.3 20 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 41.4 42.6 N.A.
Protein Similarity: N.A. N.A. N.A. 55.4 57.3 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 13 0 7 7 32 25 0 19 25 7 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 19 13 0 0 50 0 0 0 % D
% Glu: 7 0 0 7 0 7 0 0 19 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 19 13 0 0 0 0 0 0 0 % F
% Gly: 7 19 7 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 19 13 0 0 0 % I
% Lys: 19 13 0 63 50 7 50 19 7 0 0 7 57 7 38 % K
% Leu: 7 0 25 13 7 7 0 0 7 0 7 19 7 0 19 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 44 0 % M
% Asn: 0 0 7 0 19 7 0 0 0 7 0 7 0 0 0 % N
% Pro: 0 7 38 7 7 7 7 0 0 7 44 0 0 0 7 % P
% Gln: 50 50 7 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 7 7 7 13 7 7 7 50 0 0 0 0 0 25 % R
% Ser: 0 7 0 0 0 32 0 38 0 0 0 7 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 50 0 0 7 0 0 % T
% Val: 0 0 0 7 0 19 13 0 0 0 0 0 7 19 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _