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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHOU All Species: 56.67
Human Site: S68 Identified Species: 83.11
UniProt: Q7L0Q8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L0Q8 NP_067028.1 258 28218 S68 G K T S L V V S Y T T N G Y P
Chimpanzee Pan troglodytes XP_525089 191 21622 G15 L G L R Q N T G A R R S V R E
Rhesus Macaque Macaca mulatta XP_001083463 258 28214 S68 G K T S L V V S Y T T N G Y P
Dog Lupus familis XP_536354 258 28130 S68 G K T S L V V S Y T T N G Y P
Cat Felis silvestris
Mouse Mus musculus Q9EQT3 261 28335 S71 G K T S L V V S Y T T N G Y P
Rat Rattus norvegicus Q9Z1Y0 236 26147 S50 G K S S L I V S Y T C N G Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521402 305 33267 S108 I Q F D R F H S P P T L A C C
Chicken Gallus gallus Q90694 191 21254 S22 G K T C L L I S Y T T N K F P
Frog Xenopus laevis NP_001087939 243 26985 S54 G K T S L L V S Y T T N G Y P
Zebra Danio Brachydanio rerio NP_001007444 254 28260 S65 G K T S L I V S Y T T N G Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40793 191 21384 S22 G K T C L L I S Y T T N K F P
Honey Bee Apis mellifera XP_395770 272 29950 S83 G K T S L V V S Y S T N G F P
Nematode Worm Caenorhab. elegans Q05062 191 21147 S22 G K T C L L I S Y T T N K F P
Sea Urchin Strong. purpuratus XP_787983 288 32045 S84 G K T S L V V S Y T T N G Y P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38912 198 21710 S25 G K T C L L I S Y T S N T F P
Baker's Yeast Sacchar. cerevisiae P19073 191 21304 S22 G K T C L L I S Y T T N Q F P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.8 99.6 98 N.A. 90.8 55 N.A. 54.7 44.9 60.8 71.7 N.A. 44.9 43.7 44.9 51
Protein Similarity: 100 68.5 100 98.8 N.A. 93.8 72 N.A. 64.5 58.1 75.5 80.6 N.A. 57.7 62.1 57.3 63.5
P-Site Identity: 100 0 100 100 N.A. 100 80 N.A. 13.3 66.6 93.3 93.3 N.A. 66.6 86.6 66.6 100
P-Site Similarity: 100 6.6 100 100 N.A. 100 93.3 N.A. 20 86.6 100 100 N.A. 86.6 100 86.6 100
Percent
Protein Identity: N.A. N.A. N.A. 41.4 42.6 N.A.
Protein Similarity: N.A. N.A. N.A. 55.4 57.3 N.A.
P-Site Identity: N.A. N.A. N.A. 60 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % A
% Cys: 0 0 0 32 0 0 0 0 0 0 7 0 0 7 7 % C
% Asp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % E
% Phe: 0 0 7 0 0 7 0 0 0 0 0 0 0 38 0 % F
% Gly: 88 7 0 0 0 0 0 7 0 0 0 0 57 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 13 32 0 0 0 0 0 0 0 0 % I
% Lys: 0 88 0 0 0 0 0 0 0 0 0 0 19 0 0 % K
% Leu: 7 0 7 0 88 38 0 0 0 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 88 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 88 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 7 7 0 0 0 0 7 7 0 0 7 0 % R
% Ser: 0 0 7 57 0 0 0 94 0 7 7 7 0 0 0 % S
% Thr: 0 0 82 0 0 0 7 0 0 82 82 0 7 0 0 % T
% Val: 0 0 0 0 0 38 57 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 88 0 0 0 0 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _