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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SV2B All Species: 22.73
Human Site: Y488 Identified Species: 55.56
UniProt: Q7L1I2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L1I2 NP_055663.1 683 77444 Y488 D V T S T D T Y F K N C T I E
Chimpanzee Pan troglodytes XP_523160 683 77332 Y488 D V T S T D T Y F K N C T I E
Rhesus Macaque Macaca mulatta XP_001099688 865 98338 Y670 D V T S T D T Y F K N C T I E
Dog Lupus familis XP_545841 713 80895 Y518 D V T S T D T Y F K N C T I E
Cat Felis silvestris
Mouse Mus musculus Q8BG39 683 77439 Y488 D V T S T D T Y F K N C T I E
Rat Rattus norvegicus Q63564 683 77484 Y488 D V T S T D T Y F K N C T I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508236 685 78153 F490 D V T S T E T F F K N C T I E
Chicken Gallus gallus XP_425081 705 80270 F510 D V T S S E T F F E N C T I I
Frog Xenopus laevis Q2XWK0 548 60977 A364 V K P K C S L A C E Y L T V E
Zebra Danio Brachydanio rerio XP_696434 733 83469 F537 D I T S S N T F F R N C T F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 78.8 91.5 N.A. 94.8 94.8 N.A. 85.4 79.4 21.8 58.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 78.8 93.9 N.A. 97.5 97.6 N.A. 92.2 88.3 38.3 73.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 66.6 13.3 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 26.6 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 10 0 0 90 0 0 0 % C
% Asp: 90 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 20 0 0 0 20 0 0 0 0 80 % E
% Phe: 0 0 0 0 0 0 0 30 90 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 80 20 % I
% Lys: 0 10 0 10 0 0 0 0 0 70 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 90 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 90 20 10 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 90 0 70 0 90 0 0 0 0 0 100 0 0 % T
% Val: 10 80 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 60 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _