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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R4 All Species: 17.27
Human Site: S166 Identified Species: 25.33
UniProt: Q7L1T6 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L1T6 NP_057314.2 521 59474 S166 T L A K E G P S Y P S Y D W F
Chimpanzee Pan troglodytes XP_518614 839 95193 S484 T L A K E G P S Y P S Y D W F
Rhesus Macaque Macaca mulatta XP_001085835 521 59486 S166 T L A K E G P S Y P S Y D W F
Dog Lupus familis XP_532219 485 55609 Y135 E G P G S P S Y D W F Q T D S
Cat Felis silvestris
Mouse Mus musculus Q3TDX8 536 60563 S181 T L P R E G L S S P S Y D W F
Rat Rattus norvegicus Q68EJ0 520 58816 S165 T L P R E G P S S P S Y D W F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512931 509 57599 N154 S E T L A K D N T P S Y D W F
Chicken Gallus gallus Q5ZHX7 304 33589
Frog Xenopus laevis Q5PQA4 296 32646
Zebra Danio Brachydanio rerio Q502I6 527 59434 H174 A P L P A K D H R P R Y D W F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611419 535 60193 P183 I T N V I L Q P P E I V P R F
Honey Bee Apis mellifera XP_394412 1021 112094 V183 H S T S Q E N V S D G D L S N
Nematode Worm Caenorhab. elegans NP_001021784 552 62304 N178 R V E T L S D N S G I S F E H
Sea Urchin Strong. purpuratus XP_001198870 432 49074 K81 K W P D T V E K I P W Y M C K
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 S255 V G K E F T M S E V R K H A S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P11035 917 102826 I562 S A D S C W I I V H G H I Y D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 98.6 83.4 N.A. 78.7 83.3 N.A. 70.6 20.7 20.5 51.9 N.A. 34 21.6 31.3 27
Protein Similarity: 100 62 99.6 87.9 N.A. 87.6 90.5 N.A. 83.1 34.7 31.4 69.8 N.A. 52.1 33.2 49.2 43.7
P-Site Identity: 100 100 100 0 N.A. 73.3 80 N.A. 40 0 0 33.3 N.A. 6.6 0 0 13.3
P-Site Similarity: 100 100 100 0 N.A. 80 86.6 N.A. 53.3 0 0 33.3 N.A. 6.6 6.6 13.3 13.3
Percent
Protein Identity: N.A. 23.1 N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 33.7 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 19 0 13 0 0 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 7 7 0 0 19 0 7 7 0 7 44 7 7 % D
% Glu: 7 7 7 7 32 7 7 0 7 7 0 0 0 7 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 7 0 7 0 50 % F
% Gly: 0 13 0 7 0 32 0 0 0 7 13 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 7 0 7 0 7 7 0 7 % H
% Ile: 7 0 0 0 7 0 7 7 7 0 13 0 7 0 0 % I
% Lys: 7 0 7 19 0 13 0 7 0 0 0 7 0 0 7 % K
% Leu: 0 32 7 7 7 7 7 0 0 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 7 0 0 0 7 13 0 0 0 0 0 0 7 % N
% Pro: 0 7 25 7 0 7 25 7 7 50 0 0 7 0 0 % P
% Gln: 0 0 0 0 7 0 7 0 0 0 0 7 0 0 0 % Q
% Arg: 7 0 0 13 0 0 0 0 7 0 13 0 0 7 0 % R
% Ser: 13 7 0 13 7 7 7 38 25 0 38 7 0 7 13 % S
% Thr: 32 7 13 7 7 7 0 0 7 0 0 0 7 0 0 % T
% Val: 7 7 0 7 0 7 0 7 7 7 0 7 0 0 0 % V
% Trp: 0 7 0 0 0 7 0 0 0 7 7 0 0 44 0 % W
% Tyr: 0 0 0 0 0 0 0 7 19 0 0 50 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _