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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R4 All Species: 24.24
Human Site: S264 Identified Species: 35.56
UniProt: Q7L1T6 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L1T6 NP_057314.2 521 59474 S264 H P L K N H N S L I P R K D T
Chimpanzee Pan troglodytes XP_518614 839 95193 S582 H P L K N H N S L I P R K D T
Rhesus Macaque Macaca mulatta XP_001085835 521 59486 S264 H P L E N H N S L I P R K D T
Dog Lupus familis XP_532219 485 55609 K233 N H N S L I P K K D T G L N Y
Cat Felis silvestris
Mouse Mus musculus Q3TDX8 536 60563 S279 D H L E K H D S F I P K K D T
Rat Rattus norvegicus Q68EJ0 520 58816 S263 D P L E K H D S F I P K K D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512931 509 57599 S252 H P L E N H N S F I S H R D T
Chicken Gallus gallus Q5ZHX7 304 33589 G52 K Y P L P L V G K E E I S H D
Frog Xenopus laevis Q5PQA4 296 32646 E44 K Y P L P L I E K Q E I S H D
Zebra Danio Brachydanio rerio Q502I6 527 59434 T272 Q S L E H H D T F I Q C K D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611419 535 60193 N281 T Y G T H V S N R L D S S R L
Honey Bee Apis mellifera XP_394412 1021 112094 S281 E I W K S Q G S Q T I S R E T
Nematode Worm Caenorhab. elegans NP_001021784 552 62304 K276 G G K I D R S K C K I Q R R P
Sea Urchin Strong. purpuratus XP_001198870 432 49074 L179 I K W T T L G L P L D D H K K
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 R353 A P I R R A V R A P A L S N P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P11035 917 102826 R660 N L A L V N P R A K V P V Q L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 98.6 83.4 N.A. 78.7 83.3 N.A. 70.6 20.7 20.5 51.9 N.A. 34 21.6 31.3 27
Protein Similarity: 100 62 99.6 87.9 N.A. 87.6 90.5 N.A. 83.1 34.7 31.4 69.8 N.A. 52.1 33.2 49.2 43.7
P-Site Identity: 100 100 93.3 0 N.A. 53.3 60 N.A. 66.6 0 0 33.3 N.A. 0 20 0 0
P-Site Similarity: 100 100 100 13.3 N.A. 73.3 80 N.A. 80 0 0 60 N.A. 26.6 40 26.6 6.6
Percent
Protein Identity: N.A. 23.1 N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 33.7 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 7 0 0 13 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % C
% Asp: 13 0 0 0 7 0 19 0 0 7 13 7 0 44 13 % D
% Glu: 7 0 0 32 0 0 0 7 0 7 13 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % F
% Gly: 7 7 7 0 0 0 13 7 0 0 0 7 0 0 0 % G
% His: 25 13 0 0 13 44 0 0 0 0 0 7 7 13 0 % H
% Ile: 7 7 7 7 0 7 7 0 0 44 13 13 0 0 0 % I
% Lys: 13 7 7 19 13 0 0 13 19 13 0 13 38 7 7 % K
% Leu: 0 7 44 19 7 19 0 7 19 13 0 7 7 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 7 0 25 7 25 7 0 0 0 0 0 13 0 % N
% Pro: 0 38 13 0 13 0 13 0 7 7 32 7 0 0 13 % P
% Gln: 7 0 0 0 0 7 0 0 7 7 7 7 0 7 0 % Q
% Arg: 0 0 0 7 7 7 0 13 7 0 0 19 19 13 7 % R
% Ser: 0 7 0 7 7 0 13 44 0 0 7 13 25 0 0 % S
% Thr: 7 0 0 13 7 0 0 7 0 7 7 0 0 0 44 % T
% Val: 0 0 0 0 7 7 13 0 0 0 7 0 7 0 0 % V
% Trp: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _