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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R4 All Species: 15.66
Human Site: S6 Identified Species: 22.97
UniProt: Q7L1T6 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L1T6 NP_057314.2 521 59474 S6 _ _ M L N V P S Q S F P A P R
Chimpanzee Pan troglodytes XP_518614 839 95193 R324 P R R G G D A R W P W N D R S
Rhesus Macaque Macaca mulatta XP_001085835 521 59486 S6 _ _ M L N V P S Q S F P A P R
Dog Lupus familis XP_532219 485 55609
Cat Felis silvestris
Mouse Mus musculus Q3TDX8 536 60563 S6 _ _ M L N V P S Q A F P A P G
Rat Rattus norvegicus Q68EJ0 520 58816 S6 _ _ M L N V P S Q A F P A P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512931 509 57599 V6 _ _ M P E L G V L I F G E N V
Chicken Gallus gallus Q5ZHX7 304 33589
Frog Xenopus laevis Q5PQA4 296 32646
Zebra Danio Brachydanio rerio Q502I6 527 59434 A8 M L N V P S Q A F P A A G S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611419 535 60193 P8 M S D P S L K P P A S N Q P L
Honey Bee Apis mellifera XP_394412 1021 112094 G15 S L V S V M D G D G S P Q S L
Nematode Worm Caenorhab. elegans NP_001021784 552 62304 S9 N N L S V N G S S N G L F A K
Sea Urchin Strong. purpuratus XP_001198870 432 49074
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 S71 I N E L N I N S V I T T P C H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P11035 917 102826 L49 T T N Q T V F L K P A K V H D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 98.6 83.4 N.A. 78.7 83.3 N.A. 70.6 20.7 20.5 51.9 N.A. 34 21.6 31.3 27
Protein Similarity: 100 62 99.6 87.9 N.A. 87.6 90.5 N.A. 83.1 34.7 31.4 69.8 N.A. 52.1 33.2 49.2 43.7
P-Site Identity: 100 0 100 0 N.A. 84.6 84.6 N.A. 15.3 0 0 0 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 6.6 100 0 N.A. 92.3 92.3 N.A. 23 0 0 20 N.A. 26.6 20 26.6 0
Percent
Protein Identity: N.A. 23.1 N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 33.7 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 7 0 19 13 7 25 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 7 0 0 7 7 0 7 0 0 0 7 0 7 % D
% Glu: 0 0 7 0 7 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 7 0 32 0 7 0 0 % F
% Gly: 0 0 0 7 7 0 13 7 0 7 7 7 7 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % H
% Ile: 7 0 0 0 0 7 0 0 0 13 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 7 0 7 0 0 7 0 0 7 % K
% Leu: 0 13 7 32 0 13 0 7 7 0 0 7 0 0 13 % L
% Met: 13 0 32 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 13 13 0 32 7 7 0 0 7 0 13 0 7 0 % N
% Pro: 7 0 0 13 7 0 25 7 7 19 0 32 7 32 0 % P
% Gln: 0 0 0 7 0 0 7 0 25 0 0 0 13 0 7 % Q
% Arg: 0 7 7 0 0 0 0 7 0 0 0 0 0 7 13 % R
% Ser: 7 7 0 13 7 7 0 38 7 13 13 0 0 13 7 % S
% Thr: 7 7 0 0 7 0 0 0 0 0 7 7 0 0 0 % T
% Val: 0 0 7 7 13 32 0 7 7 0 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 32 32 0 0 0 0 0 0 0 0 0 0 0 0 0 % _