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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5R4 All Species: 9.09
Human Site: Y139 Identified Species: 13.33
UniProt: Q7L1T6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L1T6 NP_057314.2 521 59474 Y139 K P A V L K D Y R E E E K K V
Chimpanzee Pan troglodytes XP_518614 839 95193 Y457 K P A V L K D Y R E E E K K V
Rhesus Macaque Macaca mulatta XP_001085835 521 59486 Y139 K P A V L K D Y R E E E K K V
Dog Lupus familis XP_532219 485 55609 E108 I P K D Y H E E K K V L N G M
Cat Felis silvestris
Mouse Mus musculus Q3TDX8 536 60563 Q154 N G M L P K S Q M S D T L P R
Rat Rattus norvegicus Q68EJ0 520 58816 D138 V K P A V P K D C H E G K R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512931 509 57599 A127 A A K P V A A A K E N L E E K
Chicken Gallus gallus Q5ZHX7 304 33589
Frog Xenopus laevis Q5PQA4 296 32646
Zebra Danio Brachydanio rerio Q502I6 527 59434 E147 Q A H T E K T E S T H L N G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611419 535 60193 K156 N Y P Q L L G K C Y V G P L K
Honey Bee Apis mellifera XP_394412 1021 112094 S156 S S M E N P A S A T T N C S S
Nematode Worm Caenorhab. elegans NP_001021784 552 62304 L151 T S D D K N K L G V P S S A L
Sea Urchin Strong. purpuratus XP_001198870 432 49074 K54 G D P L A F F K V P D K K S S
Poplar Tree Populus trichocarpa
Maize Zea mays P17571 621 69754 E228 E K H L E T A E A A A P G L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P11035 917 102826 T535 S L K K S V S T P F M N T T A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 98.6 83.4 N.A. 78.7 83.3 N.A. 70.6 20.7 20.5 51.9 N.A. 34 21.6 31.3 27
Protein Similarity: 100 62 99.6 87.9 N.A. 87.6 90.5 N.A. 83.1 34.7 31.4 69.8 N.A. 52.1 33.2 49.2 43.7
P-Site Identity: 100 100 100 6.6 N.A. 6.6 20 N.A. 6.6 0 0 6.6 N.A. 6.6 0 0 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 20 33.3 N.A. 33.3 0 0 20 N.A. 6.6 0 6.6 26.6
Percent
Protein Identity: N.A. 23.1 N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 33.7 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 19 7 7 7 19 7 13 7 7 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 0 7 0 0 % C
% Asp: 0 7 7 13 0 0 19 7 0 0 13 0 0 0 0 % D
% Glu: 7 0 0 7 13 0 7 19 0 25 25 19 7 7 0 % E
% Phe: 0 0 0 0 0 7 7 0 0 7 0 0 0 0 0 % F
% Gly: 7 7 0 0 0 0 7 0 7 0 0 13 7 13 0 % G
% His: 0 0 13 0 0 7 0 0 0 7 7 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 13 19 7 7 32 13 13 13 7 0 7 32 19 19 % K
% Leu: 0 7 0 19 25 7 0 7 0 0 0 19 7 13 13 % L
% Met: 0 0 13 0 0 0 0 0 7 0 7 0 0 0 7 % M
% Asn: 13 0 0 0 7 7 0 0 0 0 7 13 13 0 0 % N
% Pro: 0 25 19 7 7 13 0 0 7 7 7 7 7 7 0 % P
% Gln: 7 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 19 0 0 0 0 7 7 % R
% Ser: 13 13 0 0 7 0 13 7 7 7 0 7 7 13 13 % S
% Thr: 7 0 0 7 0 7 7 7 0 13 7 7 7 7 0 % T
% Val: 7 0 0 19 13 7 0 0 7 7 13 0 0 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 19 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _