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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX30
All Species:
29.39
Human Site:
S549
Identified Species:
46.19
UniProt:
Q7L2E3
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2E3
NP_055781.2
1194
133938
S549
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
I484
G
N
E
V
G
Y
S
I
R
F
E
D
C
T
S
Rhesus Macaque
Macaca mulatta
XP_001113204
1194
133946
S549
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Dog
Lupus familis
XP_533844
1194
133819
S549
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99PU8
1217
136650
S572
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Rat
Rattus norvegicus
Q5BJS0
1194
133979
S549
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517092
1142
128005
S503
R
K
L
Q
S
N
P
S
L
E
G
V
S
H
V
Chicken
Gallus gallus
Q5ZI74
1231
137685
S593
R
K
L
Q
G
N
P
S
L
E
G
V
S
H
V
Frog
Xenopus laevis
Q68FK8
1262
140510
R505
R
K
L
E
S
G
I
R
G
I
S
H
V
I
V
Zebra Danio
Brachydanio rerio
XP_699339
948
106042
R388
F
G
G
C
P
V
L
R
V
P
G
F
M
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
R499
R
K
L
E
A
G
L
R
G
V
S
H
I
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
R496
R
M
M
E
N
G
L
R
G
I
S
H
V
I
I
Sea Urchin
Strong. purpuratus
XP_783104
888
100644
Q328
I
R
Q
D
M
G
S
Q
C
N
I
V
I
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
A553
T
Q
V
T
Q
Y
L
A
E
A
G
Y
T
T
K
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
T719
R
L
L
Q
N
A
R
T
M
L
E
N
T
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.7
99.5
98.7
N.A.
95.8
97.7
N.A.
80
74.1
26.5
40.7
N.A.
27.1
N.A.
26.9
31.4
Protein Similarity:
100
41.9
99.8
99.4
N.A.
97.2
99
N.A.
86.7
84.4
43.9
55.7
N.A.
43.2
N.A.
44.4
48.5
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
93.3
33.3
13.3
N.A.
26.6
N.A.
6.6
6.6
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
100
93.3
40
20
N.A.
40
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
7
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
7
0
0
0
7
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
7
20
0
0
0
0
7
47
14
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
7
7
7
0
14
27
0
0
20
0
60
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
54
0
% H
% Ile:
7
0
0
0
0
0
7
7
0
14
7
0
14
27
7
% I
% Lys:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
7
67
0
0
0
27
0
47
7
0
0
0
0
0
% L
% Met:
0
7
7
0
7
0
0
0
7
0
0
0
7
0
0
% M
% Asn:
0
7
0
0
14
47
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
7
0
47
0
0
7
0
0
0
0
7
% P
% Gln:
0
7
7
54
7
0
0
7
0
0
0
0
0
0
7
% Q
% Arg:
74
7
0
0
0
0
7
27
7
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
47
0
14
47
0
0
20
0
47
0
7
% S
% Thr:
7
0
0
7
0
0
0
7
0
0
0
0
14
20
0
% T
% Val:
0
0
7
7
0
7
0
0
7
7
0
54
14
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _