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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX30 All Species: 38.48
Human Site: S591 Identified Species: 60.48
UniProt: Q7L2E3 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L2E3 NP_055781.2 1194 133938 S591 A L R L V L M S A T G D N E R
Chimpanzee Pan troglodytes Q7YR39 1044 119631 S518 E P D L A S Y S V V M V D E A
Rhesus Macaque Macaca mulatta XP_001113204 1194 133946 S591 A L R L V L M S A T G D N E R
Dog Lupus familis XP_533844 1194 133819 S591 A L R L V L M S A T G D N E R
Cat Felis silvestris
Mouse Mus musculus Q99PU8 1217 136650 S614 A L R L V L M S A T G D N E R
Rat Rattus norvegicus Q5BJS0 1194 133979 S591 A L R L V L M S A T G D N E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517092 1142 128005 S545 G L R L V L M S A T G D N E R
Chicken Gallus gallus Q5ZI74 1231 137685 S635 D L R L V L M S A T G D N Q R
Frog Xenopus laevis Q68FK8 1262 140510 S545 E I R V I L M S A T I D T S M
Zebra Danio Brachydanio rerio XP_699339 948 106042 A422 M G S T Q W S A E E E N N V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 S539 D L H V I L M S A T I D T T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22307 1301 144195 D542 M S A T I D T D L F T N F F S
Sea Urchin Strong. purpuratus XP_783104 888 100644 Y362 K V G K T V G Y Q I R L H R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 E590 E F G C R L G E E V G Y A I R
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 S761 G M K I V L M S A T V N V D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.7 99.5 98.7 N.A. 95.8 97.7 N.A. 80 74.1 26.5 40.7 N.A. 27.1 N.A. 26.9 31.4
Protein Similarity: 100 41.9 99.8 99.4 N.A. 97.2 99 N.A. 86.7 84.4 43.9 55.7 N.A. 43.2 N.A. 44.4 48.5
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. 93.3 86.6 46.6 6.6 N.A. 46.6 N.A. 0 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 93.3 93.3 66.6 20 N.A. 66.6 N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 26 24.2 N.A.
Protein Similarity: N.A. N.A. N.A. 44.9 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. 20 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 7 0 7 0 0 7 67 0 0 0 7 0 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 7 0 0 7 0 7 0 0 0 60 7 7 0 % D
% Glu: 20 0 0 0 0 0 0 7 14 7 7 0 0 47 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 7 0 0 7 7 0 % F
% Gly: 14 7 14 0 0 0 14 0 0 0 54 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 7 0 7 20 0 0 0 0 7 14 0 0 7 0 % I
% Lys: 7 0 7 7 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 54 0 54 0 74 0 0 7 0 0 7 0 0 7 % L
% Met: 14 7 0 0 0 0 67 0 0 0 7 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 20 54 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 7 0 0 0 0 7 0 % Q
% Arg: 0 0 54 0 7 0 0 0 0 0 7 0 0 7 60 % R
% Ser: 0 7 7 0 0 7 7 74 0 0 0 0 0 7 7 % S
% Thr: 0 0 0 14 7 0 7 0 0 67 7 0 14 7 7 % T
% Val: 0 7 0 14 54 7 0 0 7 14 7 7 7 7 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 7 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _