KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
30.61
Human Site:
S178
Identified Species:
48.1
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
S178
A
L
V
D
C
K
K
S
D
A
A
S
K
V
M
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
S178
A
L
V
D
C
K
K
S
D
A
A
S
K
V
M
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
V216
L
K
E
D
D
K
D
V
E
S
V
M
N
S
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
S178
A
L
V
D
C
K
K
S
D
A
A
S
K
V
M
Rat
Rattus norvegicus
XP_215794
451
50894
S255
A
L
V
D
C
K
K
S
D
A
A
S
K
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
S336
A
L
V
D
C
K
K
S
D
T
A
S
K
V
M
Chicken
Gallus gallus
Q5ZJ64
374
42572
S178
V
L
V
D
C
K
K
S
D
T
A
A
K
V
M
Frog
Xenopus laevis
Q7ZYU8
374
42287
S178
A
L
V
D
C
K
K
S
D
E
A
A
K
V
M
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
S178
A
L
V
D
C
K
K
S
E
A
A
A
K
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
E180
V
T
K
D
T
N
L
E
L
S
S
K
V
M
I
Honey Bee
Apis mellifera
XP_393333
391
44458
G180
V
L
L
S
C
K
Q
G
E
Q
A
A
A
V
M
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
V186
A
L
L
V
D
Q
R
V
D
Q
A
A
K
V
M
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
N230
E
G
F
V
I
D
G
N
D
E
A
S
V
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
M196
I
L
K
D
H
K
G
M
A
K
E
Y
F
N
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
Q180
A
A
N
D
G
G
D
Q
E
E
S
Y
F
Y
L
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
93.3
80
86.6
86.6
N.A.
6.6
40
46.6
33.3
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
93.3
86.6
93.3
100
N.A.
33.3
66.6
73.3
40
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
7
0
0
0
0
0
0
7
34
74
34
7
0
0
% A
% Cys:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
80
14
7
14
0
60
0
0
0
0
0
0
% D
% Glu:
7
0
7
0
0
0
0
7
27
20
7
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
14
0
7
% F
% Gly:
0
7
0
0
7
7
14
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
7
14
0
0
74
54
0
0
7
0
7
60
0
0
% K
% Leu:
7
74
14
0
0
0
7
0
7
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
74
% M
% Asn:
0
0
7
0
0
7
0
7
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
7
7
0
14
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
54
0
14
14
40
0
7
0
% S
% Thr:
0
7
0
0
7
0
0
0
0
14
0
0
0
0
0
% T
% Val:
20
0
54
14
0
0
0
14
0
0
7
0
14
74
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
14
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _