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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
49.09
Human Site:
Y252
Identified Species:
77.14
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
Y252
V
S
A
K
L
A
S
Y
V
K
F
Y
Q
N
N
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
Y252
V
S
A
K
L
A
S
Y
V
K
F
Y
Q
N
N
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
T314
I
S
D
W
N
L
T
T
E
K
K
H
T
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
Y252
V
S
A
K
L
A
S
Y
V
K
F
Y
Q
N
N
Rat
Rattus norvegicus
XP_215794
451
50894
Y329
V
S
A
K
L
A
S
Y
V
K
F
Y
Q
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
Y410
V
S
A
K
L
A
S
Y
V
K
F
Y
Q
N
N
Chicken
Gallus gallus
Q5ZJ64
374
42572
Y252
V
S
A
K
L
V
S
Y
V
K
F
Y
Q
N
N
Frog
Xenopus laevis
Q7ZYU8
374
42287
Y252
V
S
A
K
L
S
S
Y
V
K
F
Y
Q
N
N
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
Y252
V
S
A
K
L
I
S
Y
V
K
F
Y
Q
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
Y253
V
S
E
K
L
P
A
Y
V
Q
F
Y
E
D
H
Honey Bee
Apis mellifera
XP_393333
391
44458
Y254
V
Q
D
K
L
P
A
Y
L
H
F
Y
Q
H
H
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
Y262
I
S
G
T
L
K
D
Y
K
E
F
V
A
K
N
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
Y166
V
S
G
R
L
E
D
Y
L
N
F
Y
N
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
Y279
L
T
K
K
L
D
S
Y
L
E
F
Q
S
A
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
Y261
T
E
Q
D
L
E
D
Y
N
D
F
R
D
E
H
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
53.3
46.6
33.3
46.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
86.6
73.3
46.6
60
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
0
34
14
0
0
0
0
0
7
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
7
0
7
20
0
0
7
0
0
7
7
0
% D
% Glu:
0
7
7
0
0
14
0
0
7
14
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
94
0
0
0
0
% F
% Gly:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
20
% H
% Ile:
14
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
74
0
7
0
0
7
60
7
0
0
7
0
% K
% Leu:
7
0
0
0
94
7
0
0
20
0
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
7
0
0
7
47
74
% N
% Pro:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
7
0
0
0
0
0
0
7
0
7
60
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
80
0
0
0
7
60
0
0
0
0
0
7
7
0
% S
% Thr:
7
7
0
7
0
0
7
7
0
0
0
0
7
0
0
% T
% Val:
74
0
0
0
0
7
0
0
60
0
0
7
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
0
0
74
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _