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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEPCE All Species: 14.55
Human Site: T287 Identified Species: 35.56
UniProt: Q7L2J0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L2J0 NP_062552.2 689 74355 T287 E S H P V P P T A P L T P L L
Chimpanzee Pan troglodytes XP_527836 689 74350 T287 E S H P V P P T A P L T P S L
Rhesus Macaque Macaca mulatta XP_001104039 689 74134 T287 E S H P V L P T A P L T P S L
Dog Lupus familis XP_546957 692 75135 T285 D S H S V L P T A P L T P S L
Cat Felis silvestris
Mouse Mus musculus Q8K3A9 666 72032 T264 S N A A V L P T D P L T P S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505557 496 54391 H129 R A P A A L A H L H A L P P Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921729 629 69161 I251 P Y E L N T S I N C R D E V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K480 1367 146215 L371 I H D P L H L L D P V D S M E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U2R0 378 44095 F9 S S H R R G S F R G R K R F Y
Sea Urchin Strong. purpuratus XP_789930 553 61051 P186 P L T K T L V P R K S S G K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.4 91.6 N.A. 87 N.A. N.A. 30.9 N.A. N.A. 43.5 N.A. 21.8 N.A. 26.4 30.6
Protein Similarity: 100 99.4 98.5 93.5 N.A. 89.6 N.A. N.A. 37.1 N.A. N.A. 56.8 N.A. 31.6 N.A. 37.4 45.7
P-Site Identity: 100 93.3 86.6 73.3 N.A. 53.3 N.A. N.A. 6.6 N.A. N.A. 0 N.A. 13.3 N.A. 13.3 0
P-Site Similarity: 100 93.3 86.6 80 N.A. 60 N.A. N.A. 13.3 N.A. N.A. 13.3 N.A. 33.3 N.A. 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 20 10 0 10 0 40 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 20 0 0 20 0 0 0 % D
% Glu: 30 0 10 0 0 0 0 0 0 0 0 0 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 10 0 0 10 0 0 % G
% His: 0 10 50 0 0 10 0 10 0 10 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 10 0 10 0 10 10 % K
% Leu: 0 10 0 10 10 50 10 10 10 0 50 10 0 10 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 20 0 10 40 0 20 50 10 0 60 0 0 60 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 10 0 0 10 10 0 0 0 20 0 20 0 10 0 0 % R
% Ser: 20 50 0 10 0 0 20 0 0 0 10 10 10 40 0 % S
% Thr: 0 0 10 0 10 10 0 50 0 0 0 50 0 0 0 % T
% Val: 0 0 0 0 50 0 10 0 0 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _