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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC37L1
All Species:
16.67
Human Site:
S274
Identified Species:
30.56
UniProt:
Q7L3B6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L3B6
NP_060383.2
337
38835
S274
K
S
R
V
R
L
Y
S
Q
S
Q
S
F
Q
P
Chimpanzee
Pan troglodytes
XP_528531
337
38812
S274
K
S
R
V
R
L
Y
S
Q
S
Q
S
F
Q
P
Rhesus Macaque
Macaca mulatta
XP_001085222
337
38862
S274
K
S
R
V
R
L
Y
S
Q
S
Q
S
F
H
P
Dog
Lupus familis
XP_533542
337
38862
S274
K
S
R
V
R
L
Y
S
Q
S
P
S
F
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZP7
335
38421
A273
K
S
R
V
R
L
Y
A
Q
S
Q
S
L
Q
P
Rat
Rattus norvegicus
Q5XIC3
335
38296
A273
K
A
R
V
R
L
Y
A
Q
S
Q
S
F
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505315
291
34050
S228
K
S
R
V
R
H
Y
S
Q
S
Q
N
Y
P
A
Chicken
Gallus gallus
O57476
393
45590
A272
K
E
R
V
R
G
R
A
K
A
R
I
E
R
A
Frog
Xenopus laevis
NP_001121204
278
32022
I215
A
F
K
S
E
L
E
I
L
K
S
K
V
R
Q
Zebra Danio
Brachydanio rerio
A7YY97
313
36353
P251
K
E
V
F
E
S
L
P
Q
E
L
K
T
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24276
389
45131
E278
I
A
Q
A
E
E
E
E
R
K
E
R
L
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02108
370
42687
A268
E
D
R
L
R
T
R
A
Q
T
K
R
D
A
A
Sea Urchin
Strong. purpuratus
XP_790817
381
44030
A262
K
E
R
V
R
G
R
A
K
V
R
I
D
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
95.5
N.A.
88.7
87.2
N.A.
71.8
33
53.4
44.8
N.A.
29
N.A.
22.1
28.8
Protein Similarity:
100
99.4
99.1
97.9
N.A.
92.5
91.3
N.A.
80.1
51.6
66.7
60.5
N.A.
46.7
N.A.
46.2
50.1
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
80
N.A.
66.6
26.6
6.6
13.3
N.A.
6.6
N.A.
20
26.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
80
60
20
13.3
N.A.
33.3
N.A.
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
0
0
0
39
0
8
0
0
0
16
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% D
% Glu:
8
24
0
0
24
8
16
8
0
8
8
0
8
0
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
39
0
0
% F
% Gly:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
16
0
0
8
% I
% Lys:
77
0
8
0
0
0
0
0
16
16
8
16
0
8
0
% K
% Leu:
0
0
0
8
0
54
8
0
8
0
8
0
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
54
% P
% Gln:
0
0
8
0
0
0
0
0
70
0
47
0
0
31
8
% Q
% Arg:
0
0
77
0
77
0
24
0
8
0
16
16
0
16
0
% R
% Ser:
0
47
0
8
0
8
0
39
0
54
8
47
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% T
% Val:
0
0
8
70
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
54
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _