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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSRC2 All Species: 27.88
Human Site: S412 Identified Species: 55.76
UniProt: Q7L4I2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L4I2 NP_937992.1 434 50560 S412 A Q Y E M A R S Q T H T Q R G
Chimpanzee Pan troglodytes XP_001168020 414 48246 S392 A Q Y E M A R S Q T H T Q R G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849465 434 50541 S412 A Q Y E M A R S Q T H T Q R G
Cat Felis silvestris
Mouse Mus musculus A2RTL5 376 43858 S354 A Q Y E M A R S Q T H T Q R G
Rat Rattus norvegicus Q5PQR4 376 43872 S354 A Q Y E M A R S Q T H T Q R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506698 476 55542 S454 A Q Y E M A R S Q T H T Q R G
Chicken Gallus gallus XP_417747 444 51135 P418 R S K S V S K P R S R S K S R
Frog Xenopus laevis Q7ZYR8 350 40306 Q329 Q Y E M A R S Q T H T Q R G M
Zebra Danio Brachydanio rerio Q6NWI1 407 46584 S383 V Q Y E M A R S Q T H T Q R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10021 208 23961 S187 R S V S R G R S H S R D G S N
Sea Urchin Strong. purpuratus XP_798233 594 64431 I555 H D Y Q T A R I K T H T Q R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23212 573 63533 A507 Q E G G K F G A L T N V V I P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.8 N.A. 99 N.A. 82.9 82.7 N.A. 88 22.5 67.2 67.2 N.A. N.A. N.A. 23.7 26.7
Protein Similarity: 100 88.7 N.A. 99.7 N.A. 85.7 85.4 N.A. 90.1 38 75.1 78.3 N.A. N.A. N.A. 32.7 41.2
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 0 0 93.3 N.A. N.A. N.A. 13.3 53.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 46.6 6.6 93.3 N.A. N.A. N.A. 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 9 67 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 9 9 59 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 0 9 9 0 0 0 0 0 9 9 59 % G
% His: 9 0 0 0 0 0 0 0 9 9 67 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % I
% Lys: 0 0 9 0 9 0 9 0 9 0 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 9 59 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % P
% Gln: 17 59 0 9 0 0 0 9 59 0 0 9 67 0 0 % Q
% Arg: 17 0 0 0 9 9 75 0 9 0 17 0 9 67 9 % R
% Ser: 0 17 0 17 0 9 9 67 0 17 0 9 0 17 9 % S
% Thr: 0 0 0 0 9 0 0 0 9 75 9 67 0 0 0 % T
% Val: 9 0 9 0 9 0 0 0 0 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 67 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _