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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSRC2 All Species: 8.79
Human Site: Y40 Identified Species: 17.58
UniProt: Q7L4I2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L4I2 NP_937992.1 434 50560 Y40 P R A S K H H Y S R S R S R S
Chimpanzee Pan troglodytes XP_001168020 414 48246 A40 N T G A G A E A K R T N F F L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849465 434 50541 Y40 P R A S K H H Y S R S R S R S
Cat Felis silvestris
Mouse Mus musculus A2RTL5 376 43858 R40 E H S S D K G R E R L N S S E
Rat Rattus norvegicus Q5PQR4 376 43872 R40 E H S S D K G R E R L N S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506698 476 55542 Y81 P R T S K H H Y S R S R S R S
Chicken Gallus gallus XP_417747 444 51135 W86 N L S S R C S W Q D L K D Y M
Frog Xenopus laevis Q7ZYR8 350 40306 K17 Q A R R H E V K A K S S K K H
Zebra Danio Brachydanio rerio Q6NWI1 407 46584 E40 R S R S R S T E R K R K S G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10021 208 23961
Sea Urchin Strong. purpuratus XP_798233 594 64431 E43 H S A S E D H E H K A D P L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23212 573 63533 K52 E R E T S R S K D R E R E K G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.8 N.A. 99 N.A. 82.9 82.7 N.A. 88 22.5 67.2 67.2 N.A. N.A. N.A. 23.7 26.7
Protein Similarity: 100 88.7 N.A. 99.7 N.A. 85.7 85.4 N.A. 90.1 38 75.1 78.3 N.A. N.A. N.A. 32.7 41.2
P-Site Identity: 100 6.6 N.A. 100 N.A. 20 20 N.A. 93.3 6.6 6.6 13.3 N.A. N.A. N.A. 0 20
P-Site Similarity: 100 20 N.A. 100 N.A. 26.6 26.6 N.A. 93.3 33.3 26.6 33.3 N.A. N.A. N.A. 0 46.6
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 25 9 0 9 0 9 9 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 17 9 0 0 9 9 0 9 9 0 9 % D
% Glu: 25 0 9 0 9 9 9 17 17 0 9 0 9 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % F
% Gly: 0 0 9 0 9 0 17 0 0 0 0 0 0 9 9 % G
% His: 9 17 0 0 9 25 34 0 9 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 25 17 0 17 9 25 0 17 9 17 0 % K
% Leu: 0 9 0 0 0 0 0 0 0 0 25 0 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 17 0 0 0 0 0 0 0 0 0 0 25 0 0 9 % N
% Pro: 25 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 9 34 17 9 17 9 0 17 9 59 9 34 0 25 0 % R
% Ser: 0 17 25 67 9 9 17 0 25 0 34 9 50 17 25 % S
% Thr: 0 9 9 9 0 0 9 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 25 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _