KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYFIP1
All Species:
40.61
Human Site:
S674
Identified Species:
68.72
UniProt:
Q7L576
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L576
NP_001028200.1
1253
145182
S674
S
L
D
L
Y
N
D
S
A
H
Y
A
L
T
R
Chimpanzee
Pan troglodytes
XP_001137120
1278
148380
S698
P
L
D
L
Y
N
D
S
A
Y
Y
A
L
T
K
Rhesus Macaque
Macaca mulatta
XP_001105005
1359
156392
S779
P
L
D
L
Y
N
D
S
A
Y
Y
A
L
T
K
Dog
Lupus familis
XP_536156
1212
140594
S674
S
L
D
L
Y
N
D
S
A
H
Y
A
L
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMB8
1253
145223
S674
S
L
D
L
Y
N
D
S
A
H
Y
A
L
T
K
Rat
Rattus norvegicus
NP_001100987
1253
145239
S674
S
L
D
L
Y
N
D
S
A
H
Y
A
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508077
1255
145699
S675
P
L
D
L
Y
N
D
S
A
Y
Y
A
L
T
K
Chicken
Gallus gallus
XP_414567
1253
145683
S673
P
L
D
L
Y
N
D
S
A
Y
Y
A
L
T
K
Frog
Xenopus laevis
Q6GQD1
1253
145619
S673
P
L
D
L
Y
N
D
S
A
Y
Y
A
L
T
K
Zebra Danio
Brachydanio rerio
Q90YM8
1253
145156
S674
S
L
D
L
Y
N
D
S
A
H
Y
A
L
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF87
1291
149242
H669
M
P
W
I
L
T
D
H
I
L
Q
T
K
E
P
Honey Bee
Apis mellifera
XP_395632
1292
149877
H671
M
P
W
I
L
T
D
H
I
L
R
S
K
E
P
Nematode Worm
Caenorhab. elegans
O44518
1262
144995
A676
Q
L
D
L
Y
N
D
A
A
Q
Y
S
L
F
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5S2C3
1283
145467
Y682
V
L
L
P
F
D
I
Y
N
D
S
A
Q
Q
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
81
96
N.A.
99
99.1
N.A.
87.4
87.7
86.9
92.5
N.A.
65.4
67.8
51.7
N.A.
Protein Similarity:
100
92.1
86.9
96.4
N.A.
99.6
99.7
N.A.
93.7
94
93.8
96.9
N.A.
80.4
81.2
70.8
N.A.
P-Site Identity:
100
80
80
100
N.A.
93.3
93.3
N.A.
80
80
80
93.3
N.A.
6.6
6.6
60
N.A.
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
93.3
93.3
93.3
100
N.A.
13.3
20
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
79
0
0
79
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
79
0
0
8
93
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
15
0
36
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
8
0
15
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
58
% K
% Leu:
0
86
8
79
15
0
0
0
0
15
0
0
79
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
79
0
0
8
0
0
0
0
0
8
% N
% Pro:
36
15
0
8
0
0
0
0
0
0
0
0
0
0
15
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
8
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
15
% R
% Ser:
36
0
0
0
0
0
0
72
0
0
8
15
0
0
0
% S
% Thr:
0
0
0
0
0
15
0
0
0
0
0
8
0
72
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
79
0
0
8
0
36
79
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _