KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
14.85
Human Site:
S237
Identified Species:
27.22
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
S237
Q
I
V
G
T
P
G
S
S
G
E
T
T
Q
P
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
S236
Q
I
V
G
T
P
G
S
S
G
E
T
T
Q
P
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
S236
Q
M
V
G
T
P
G
S
S
G
E
A
A
Q
P
Dog
Lupus familis
XP_544256
875
97644
S236
Q
N
A
G
T
P
R
S
S
G
E
P
A
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
D253
V
S
P
G
N
S
G
D
R
P
Q
Q
V
S
Q
Rat
Rattus norvegicus
NP_001100836
889
98964
E257
A
T
P
G
N
P
G
E
P
S
P
Q
V
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
M128
S
A
E
M
D
R
K
M
A
N
R
K
L
I
R
Frog
Xenopus laevis
Q5EAW4
860
95399
L228
T
Q
P
I
T
N
T
L
K
S
P
V
G
Q
Q
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
S222
E
V
A
V
E
K
F
S
G
L
R
L
R
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
S175
P
V
A
A
A
V
A
S
T
S
Q
S
S
A
P
Honey Bee
Apis mellifera
XP_001121461
641
73638
E40
N
N
K
S
L
P
K
E
T
L
K
E
L
D
F
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
P90
K
N
S
S
T
S
G
P
K
A
T
D
A
W
K
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
E102
R
K
P
M
K
E
E
E
A
C
E
T
E
Y
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
80
60
N.A.
13.3
20
N.A.
N.A.
0
13.3
13.3
N.A.
13.3
6.6
13.3
13.3
P-Site Similarity:
100
100
86.6
60
N.A.
20
20
N.A.
N.A.
6.6
13.3
33.3
N.A.
46.6
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
24
8
8
0
8
0
16
8
0
8
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
8
0
8
0
% D
% Glu:
8
0
8
0
8
8
8
24
0
0
39
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% F
% Gly:
0
0
0
47
0
0
47
0
8
31
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
8
8
16
0
16
0
8
8
0
8
8
% K
% Leu:
0
0
0
0
8
0
0
8
0
16
0
8
16
0
0
% L
% Met:
0
8
0
16
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
24
0
0
16
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
31
0
0
47
0
8
8
8
16
8
0
8
39
% P
% Gln:
31
8
0
0
0
0
0
0
0
0
16
16
0
39
24
% Q
% Arg:
8
0
0
0
0
8
8
0
8
0
16
0
8
0
8
% R
% Ser:
8
8
8
16
0
16
0
47
31
24
0
8
8
8
0
% S
% Thr:
8
8
0
0
47
0
8
0
16
0
8
24
16
0
8
% T
% Val:
8
16
24
8
0
8
0
0
0
0
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _