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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
6.67
Human Site:
T242
Identified Species:
12.22
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
T242
P
G
S
S
G
E
T
T
Q
P
I
C
V
E
A
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
T241
P
G
S
S
G
E
T
T
Q
P
I
C
V
E
A
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
A241
P
G
S
S
G
E
A
A
Q
P
I
C
V
E
A
Dog
Lupus familis
XP_544256
875
97644
A241
P
R
S
S
G
E
P
A
Q
T
V
V
S
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
V258
S
G
D
R
P
Q
Q
V
S
Q
V
S
V
E
A
Rat
Rattus norvegicus
NP_001100836
889
98964
V262
P
G
E
P
S
P
Q
V
P
Q
V
S
V
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
L133
R
K
M
A
N
R
K
L
I
R
L
S
Q
L
K
Frog
Xenopus laevis
Q5EAW4
860
95399
G233
N
T
L
K
S
P
V
G
Q
Q
Y
H
V
E
K
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
R227
K
F
S
G
L
R
L
R
K
P
R
L
S
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
S180
V
A
S
T
S
Q
S
S
A
P
V
S
A
V
F
Honey Bee
Apis mellifera
XP_001121461
641
73638
L45
P
K
E
T
L
K
E
L
D
F
N
F
L
D
K
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
A95
S
G
P
K
A
T
D
A
W
K
T
N
K
K
S
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
E107
E
E
E
A
C
E
T
E
Y
F
S
R
I
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
86.6
40
N.A.
26.6
33.3
N.A.
N.A.
0
20
13.3
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
86.6
46.6
N.A.
40
40
N.A.
N.A.
13.3
20
20
N.A.
46.6
33.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
8
0
8
24
8
0
0
0
8
0
39
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
24
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
8
0
0
0
0
8
0
% D
% Glu:
8
8
24
0
0
39
8
8
0
0
0
0
0
47
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
16
0
8
0
0
8
% F
% Gly:
0
47
0
8
31
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
24
0
8
0
16
% I
% Lys:
8
16
0
16
0
8
8
0
8
8
0
0
8
8
24
% K
% Leu:
0
0
8
0
16
0
8
16
0
0
8
8
8
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
47
0
8
8
8
16
8
0
8
39
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
16
0
39
24
0
0
8
0
0
% Q
% Arg:
8
8
0
8
0
16
0
8
0
8
8
8
0
8
0
% R
% Ser:
16
0
47
31
24
0
8
8
8
0
8
31
16
8
8
% S
% Thr:
0
8
0
16
0
8
24
16
0
8
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
16
0
0
31
8
47
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _