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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
14.55
Human Site:
T623
Identified Species:
26.67
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
T623
R
L
E
G
A
P
A
T
M
T
P
K
L
G
R
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
T622
R
L
E
G
A
P
A
T
M
T
P
K
L
G
R
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
T622
R
L
E
G
A
L
A
T
M
T
P
K
L
G
R
Dog
Lupus familis
XP_544256
875
97644
T623
S
L
E
G
A
P
A
T
Q
M
P
K
L
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
P635
R
L
E
G
T
A
T
P
R
M
P
K
L
G
R
Rat
Rattus norvegicus
NP_001100836
889
98964
P639
R
L
E
G
T
E
A
P
W
T
P
K
L
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
A504
T
P
K
L
D
S
L
A
E
A
K
K
L
A
A
Frog
Xenopus laevis
Q5EAW4
860
95399
A610
F
P
N
A
Q
K
M
A
T
P
K
L
G
R
G
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
D602
E
G
E
D
I
V
F
D
M
S
P
P
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
V551
N
F
S
F
E
I
N
V
G
S
R
Q
A
Q
N
Honey Bee
Apis mellifera
XP_001121461
641
73638
P416
G
I
I
D
L
S
E
P
I
T
K
K
Q
I
N
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
S466
A
T
S
G
T
S
A
S
S
P
G
G
S
K
L
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
T478
N
K
R
S
G
A
S
T
L
I
A
K
Q
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
93.3
80
N.A.
60
73.3
N.A.
N.A.
13.3
0
20
N.A.
0
13.3
13.3
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
60
73.3
N.A.
N.A.
20
0
33.3
N.A.
13.3
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
31
16
47
16
0
8
8
0
8
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
54
0
8
8
8
0
8
0
0
0
0
0
0
% E
% Phe:
8
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
54
8
0
0
0
8
0
8
8
8
47
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
8
8
0
0
8
0
0
0
0
24
70
0
8
8
% K
% Leu:
0
47
0
8
8
8
8
0
8
0
0
8
54
0
8
% L
% Met:
0
0
0
0
0
0
8
0
31
16
0
0
0
0
0
% M
% Asn:
16
0
8
0
0
0
8
0
0
0
0
0
0
0
16
% N
% Pro:
0
16
0
0
0
24
0
24
0
16
54
8
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
8
16
8
0
% Q
% Arg:
39
0
8
0
0
0
0
0
8
0
8
0
0
16
47
% R
% Ser:
8
0
16
8
0
24
8
8
8
16
0
0
16
8
0
% S
% Thr:
8
8
0
0
24
0
8
39
8
39
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _