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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
16.06
Human Site:
Y411
Identified Species:
29.44
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
Y411
V
N
L
R
D
C
E
Y
C
Q
Y
H
V
Q
A
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
Y410
V
N
L
R
D
C
E
Y
C
Q
Y
H
V
Q
A
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
Y410
V
N
L
R
D
C
E
Y
C
Q
Y
H
V
Q
A
Dog
Lupus familis
XP_544256
875
97644
Y411
V
N
L
N
D
C
E
Y
C
Q
Y
H
I
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
E426
T
V
N
L
H
D
C
E
Y
C
Q
Y
H
I
Q
Rat
Rattus norvegicus
NP_001100836
889
98964
E430
T
V
N
L
H
D
C
E
Y
C
Q
Y
H
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
K295
I
P
K
K
L
G
R
K
N
P
S
L
K
E
R
Frog
Xenopus laevis
Q5EAW4
860
95399
E401
M
V
N
L
N
D
C
E
Y
C
Q
Y
H
V
Q
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
Y391
Q
Y
H
V
K
A
Q
Y
K
K
M
S
S
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
T342
K
K
N
G
D
K
C
T
S
V
V
N
L
T
D
Honey Bee
Apis mellifera
XP_001121461
641
73638
L207
F
S
N
A
H
K
T
L
W
K
T
T
I
G
T
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
I257
K
S
N
N
I
V
E
I
G
Q
S
A
H
F
G
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
S269
C
S
Q
I
I
N
T
S
D
C
Q
Y
C
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
86.6
N.A.
0
0
N.A.
N.A.
0
0
6.6
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
20
20
26.6
N.A.
20
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
0
0
8
0
8
31
% A
% Cys:
8
0
0
0
0
31
31
0
31
31
0
0
8
0
0
% C
% Asp:
0
0
0
0
39
24
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
39
24
0
0
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
8
0
0
8
0
0
0
0
8
8
% G
% His:
0
0
8
0
24
0
0
0
0
0
0
31
31
0
0
% H
% Ile:
8
0
0
8
16
0
0
8
0
0
0
0
16
16
0
% I
% Lys:
16
8
8
8
8
16
0
8
8
16
0
0
8
8
0
% K
% Leu:
0
0
31
24
8
0
0
8
0
0
0
8
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
31
47
16
8
8
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
8
0
0
39
31
0
0
31
24
% Q
% Arg:
0
0
0
24
0
0
8
0
0
0
0
0
0
0
16
% R
% Ser:
0
24
0
0
0
0
0
8
8
0
16
8
8
0
0
% S
% Thr:
16
0
0
0
0
0
16
8
0
0
8
8
0
8
8
% T
% Val:
31
24
0
8
0
8
0
0
0
8
8
0
24
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
39
24
0
31
31
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _