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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM10
All Species:
9.09
Human Site:
Y641
Identified Species:
16.67
UniProt:
Q7L590
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L590
NP_060988.3
875
98183
Y641
E
G
D
D
V
L
F
Y
D
E
S
P
P
P
R
Chimpanzee
Pan troglodytes
XP_001140870
874
98112
Y640
E
G
D
D
V
L
F
Y
D
E
S
P
P
P
R
Rhesus Macaque
Macaca mulatta
XP_001085751
873
97875
Y640
E
G
D
D
V
L
F
Y
D
E
S
P
P
P
R
Dog
Lupus familis
XP_544256
875
97644
F641
E
G
D
D
V
L
F
F
D
E
S
P
P
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBD2
885
98387
F653
E
G
D
D
V
L
F
F
D
D
S
P
P
P
R
Rat
Rattus norvegicus
NP_001100836
889
98964
F657
D
G
D
D
V
L
F
F
D
E
S
P
P
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423055
729
81488
I521
R
L
R
A
K
G
H
I
L
D
K
T
D
P
N
Frog
Xenopus laevis
Q5EAW4
860
95399
F627
E
G
D
D
V
L
F
F
D
I
S
P
P
P
A
Zebra Danio
Brachydanio rerio
Q5RHY1
833
92421
V619
S
A
T
K
L
A
A
V
R
K
L
Q
A
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIE6
776
86505
K568
L
K
A
A
A
L
L
K
K
K
P
L
E
K
I
Honey Bee
Apis mellifera
XP_001121461
641
73638
V433
K
R
N
A
V
N
W
V
K
E
N
G
K
I
K
Nematode Worm
Caenorhab. elegans
NP_499456
691
76034
A483
M
S
L
A
N
K
K
A
A
P
L
G
H
K
D
Sea Urchin
Strong. purpuratus
XP_782384
703
78261
I495
V
I
H
K
K
G
G
I
A
K
E
D
P
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
83.1
N.A.
74.6
76.8
N.A.
N.A.
53.5
58
45.9
N.A.
28.6
27.2
25
29.3
Protein Similarity:
100
99.5
97.4
90.7
N.A.
84.7
86.1
N.A.
N.A.
66.1
72.8
62.9
N.A.
47.4
44.4
42.6
45.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
N.A.
6.6
80
0
N.A.
6.6
13.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
86.6
13.3
N.A.
13.3
46.6
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
31
8
8
8
8
16
0
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
54
54
0
0
0
0
54
16
0
8
8
0
8
% D
% Glu:
47
0
0
0
0
0
0
0
0
47
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
54
31
0
0
0
0
0
0
0
% F
% Gly:
0
54
0
0
0
16
8
0
0
0
0
16
0
0
8
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
16
0
8
0
0
0
8
8
% I
% Lys:
8
8
0
16
16
8
8
8
16
24
8
0
8
24
16
% K
% Leu:
8
8
8
0
8
62
8
0
8
0
16
8
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
0
0
0
0
8
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
54
62
62
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
8
8
0
0
0
0
0
8
0
0
0
0
0
39
% R
% Ser:
8
8
0
0
0
0
0
0
0
0
54
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
8
0
0
0
62
0
0
16
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _