KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1539
All Species:
15.76
Human Site:
S131
Identified Species:
38.52
UniProt:
Q7L5A3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5A3
NP_079458.2
538
56690
S131
C
V
V
E
Q
R
S
S
V
T
S
S
W
T
S
Chimpanzee
Pan troglodytes
XP_001165916
538
56738
S131
C
V
V
E
Q
R
S
S
V
T
S
S
W
T
S
Rhesus Macaque
Macaca mulatta
XP_001090314
538
56684
S131
C
V
V
E
Q
R
S
S
V
T
S
S
W
T
S
Dog
Lupus familis
XP_852785
536
56436
S129
C
V
V
E
Q
G
G
S
S
T
S
P
W
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BR27
538
57056
N131
C
V
V
E
H
G
G
N
T
T
S
P
W
T
S
Rat
Rattus norvegicus
Q5PQM8
538
56972
S131
R
V
V
E
Q
G
G
S
A
T
S
S
W
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI58
1093
122387
V376
L
L
Q
E
R
Q
E
V
I
A
R
I
A
Q
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LV22
1021
113458
W219
A
A
D
E
E
L
I
W
N
F
S
Q
T
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610688
1297
137494
N213
S
S
A
G
G
G
T
N
N
S
S
A
A
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799179
409
45632
D18
T
K
G
A
S
R
G
D
V
P
L
D
E
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.6
93.6
N.A.
91
91.8
N.A.
N.A.
25.6
N.A.
25.7
N.A.
21.1
N.A.
N.A.
29.7
Protein Similarity:
100
99
98.6
95.1
N.A.
92.9
93.4
N.A.
N.A.
34.7
N.A.
34.7
N.A.
27.6
N.A.
N.A.
44.2
P-Site Identity:
100
100
100
73.3
N.A.
60
73.3
N.A.
N.A.
6.6
N.A.
20
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
N.A.
33.3
N.A.
26.6
N.A.
46.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
0
0
10
10
0
10
20
0
10
% A
% Cys:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
80
10
0
10
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
10
10
10
40
40
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
20
20
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
20
0
10
0
% P
% Gln:
0
0
10
0
50
10
0
0
0
0
0
10
0
10
0
% Q
% Arg:
10
0
0
0
10
40
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
10
0
0
10
0
30
50
10
10
80
40
0
10
80
% S
% Thr:
10
0
0
0
0
0
10
0
10
60
0
0
10
60
0
% T
% Val:
0
60
60
0
0
0
0
10
40
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
60
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _