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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FA2H All Species: 25.15
Human Site: S201 Identified Species: 46.11
UniProt: Q7L5A8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L5A8 NP_077282.3 372 42791 S201 G N V R L F T S F T T E Y T V
Chimpanzee Pan troglodytes XP_511106 332 38028 T167 L I E G L S K T V W Y S V P I
Rhesus Macaque Macaca mulatta XP_001108607 372 42764 S201 G N V R L F T S F T T E Y A L
Dog Lupus familis XP_853014 372 42728 S201 G N V R L F E S F S T E Y S V
Cat Felis silvestris
Mouse Mus musculus Q5MPP0 372 42963 S201 D N I R L F A S L T R E Y S M
Rat Rattus norvegicus Q2LAM0 372 42655 S201 D N I R L F A S F T R D Y S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414053 365 42262 S194 G N T R L F S S F T T E Y S I
Frog Xenopus laevis NP_001082707 369 42797 S199 G N T R I F S S F T K D Y S V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122312 313 37178 I148 Y V I P L V W I P I S I Y F F
Nematode Worm Caenorhab. elegans NP_492678 316 36308 F151 S I L S V L S F S T S T D V Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330558 236 27174 L71 P V I C Y F V L K S V R M G H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_181023 237 27404 R72 V V V W C I S R S V S M G C S
Baker's Yeast Sacchar. cerevisiae Q03529 384 44863 Y211 A W L P V V V Y H M G V A L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.1 97.5 81.4 N.A. 82.5 81.1 N.A. N.A. 67.7 59.6 N.A. N.A. N.A. 32.2 35.2 N.A.
Protein Similarity: 100 80.3 98.9 91.6 N.A. 89.7 89.2 N.A. N.A. 79 72.8 N.A. N.A. N.A. 50.8 52.6 N.A.
P-Site Identity: 100 6.6 86.6 80 N.A. 53.3 53.3 N.A. N.A. 73.3 60 N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 100 20 93.3 93.3 N.A. 73.3 80 N.A. N.A. 93.3 86.6 N.A. N.A. N.A. 26.6 33.3 N.A.
Percent
Protein Identity: 29.8 N.A. N.A. 28.7 27.8 N.A.
Protein Similarity: 43.2 N.A. N.A. 42.7 47.1 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 16 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 16 0 0 0 0 0 0 0 0 0 0 16 8 0 0 % D
% Glu: 0 0 8 0 0 0 8 0 0 0 0 39 0 0 0 % E
% Phe: 0 0 0 0 0 62 0 8 47 0 0 0 0 8 8 % F
% Gly: 39 0 0 8 0 0 0 0 0 0 8 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % H
% Ile: 0 16 31 0 8 8 0 8 0 8 0 8 0 0 16 % I
% Lys: 0 0 0 0 0 0 8 0 8 0 8 0 0 0 8 % K
% Leu: 8 0 16 0 62 8 0 8 8 0 0 0 0 8 16 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 8 8 0 8 % M
% Asn: 0 54 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 16 0 0 0 0 8 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 54 0 0 0 8 0 0 16 8 0 0 0 % R
% Ser: 8 0 0 8 0 8 31 54 16 16 24 8 0 39 8 % S
% Thr: 0 0 16 0 0 0 16 8 0 54 31 8 0 8 0 % T
% Val: 8 24 31 0 16 16 16 0 8 8 8 8 8 8 24 % V
% Trp: 0 8 0 8 0 0 8 0 0 8 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 8 0 0 8 0 62 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _