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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FA2H
All Species:
28.79
Human Site:
Y141
Identified Species:
52.78
UniProt:
Q7L5A8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5A8
NP_077282.3
372
42791
Y141
V
G
H
L
G
E
K
Y
D
E
W
V
H
Q
P
Chimpanzee
Pan troglodytes
XP_511106
332
38028
E107
L
G
Q
L
P
G
F
E
P
C
M
Q
P
R
S
Rhesus Macaque
Macaca mulatta
XP_001108607
372
42764
Y141
V
G
H
L
G
E
K
Y
D
E
W
V
H
Q
P
Dog
Lupus familis
XP_853014
372
42728
Y141
V
G
H
L
G
E
K
Y
D
E
W
V
H
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5MPP0
372
42963
Y141
V
G
H
L
G
E
K
Y
D
E
W
V
H
Q
P
Rat
Rattus norvegicus
Q2LAM0
372
42655
Y141
V
G
H
L
G
E
K
Y
D
E
W
V
H
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414053
365
42262
Y134
V
G
Y
L
G
E
K
Y
D
E
W
V
H
Q
P
Frog
Xenopus laevis
NP_001082707
369
42797
Y139
V
G
H
L
R
E
K
Y
D
E
W
V
H
Q
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122312
313
37178
Y88
T
L
K
N
E
E
K
Y
Q
K
Y
E
N
L
I
Nematode Worm
Caenorhab. elegans
NP_492678
316
36308
L91
I
E
S
K
S
G
M
L
F
K
V
G
S
L
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330558
236
27174
D11
Q
E
F
T
V
D
L
D
K
P
L
V
F
Q
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181023
237
27404
K12
G
F
T
V
D
L
K
K
P
L
V
F
Q
V
G
Baker's Yeast
Sacchar. cerevisiae
Q03529
384
44863
N151
K
H
K
F
L
D
L
N
R
P
L
L
M
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
97.5
81.4
N.A.
82.5
81.1
N.A.
N.A.
67.7
59.6
N.A.
N.A.
N.A.
32.2
35.2
N.A.
Protein Similarity:
100
80.3
98.9
91.6
N.A.
89.7
89.2
N.A.
N.A.
79
72.8
N.A.
N.A.
N.A.
50.8
52.6
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
N.A.
N.A.
N.A.
40
13.3
N.A.
Percent
Protein Identity:
29.8
N.A.
N.A.
28.7
27.8
N.A.
Protein Similarity:
43.2
N.A.
N.A.
42.7
47.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
16
0
8
54
0
0
0
0
0
0
% D
% Glu:
0
16
0
0
8
62
0
8
0
54
0
8
0
0
0
% E
% Phe:
0
8
8
8
0
0
8
0
8
0
0
8
8
0
0
% F
% Gly:
8
62
0
0
47
16
0
0
0
0
0
8
0
0
16
% G
% His:
0
8
47
0
0
0
0
0
0
0
0
0
54
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
8
0
16
8
0
0
70
8
8
16
0
0
0
0
0
% K
% Leu:
8
8
0
62
8
8
16
8
0
8
16
8
0
16
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
16
16
0
0
8
0
54
% P
% Gln:
8
0
8
0
0
0
0
0
8
0
0
8
8
70
0
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
8
% S
% Thr:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
54
0
0
8
8
0
0
0
0
0
16
62
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _