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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FA2H
All Species:
23.33
Human Site:
Y206
Identified Species:
42.78
UniProt:
Q7L5A8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5A8
NP_077282.3
372
42791
Y206
F
T
S
F
T
T
E
Y
T
V
A
V
P
K
S
Chimpanzee
Pan troglodytes
XP_511106
332
38028
V172
S
K
T
V
W
Y
S
V
P
I
I
W
V
P
L
Rhesus Macaque
Macaca mulatta
XP_001108607
372
42764
Y206
F
T
S
F
T
T
E
Y
A
L
A
V
P
K
S
Dog
Lupus familis
XP_853014
372
42728
Y206
F
E
S
F
S
T
E
Y
S
V
A
M
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5MPP0
372
42963
Y206
F
A
S
L
T
R
E
Y
S
M
M
M
P
E
S
Rat
Rattus norvegicus
Q2LAM0
372
42655
Y206
F
A
S
F
T
R
D
Y
S
L
V
V
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414053
365
42262
Y199
F
S
S
F
T
T
E
Y
S
I
P
V
H
K
Y
Frog
Xenopus laevis
NP_001082707
369
42797
Y204
F
S
S
F
T
K
D
Y
S
V
P
V
P
V
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122312
313
37178
Y153
V
W
I
P
I
S
I
Y
F
F
Y
L
G
W
M
Nematode Worm
Caenorhab. elegans
NP_492678
316
36308
D156
L
S
F
S
T
S
T
D
V
Y
N
S
I
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330558
236
27174
M76
F
V
L
K
S
V
R
M
G
H
T
L
S
E
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181023
237
27404
G77
I
S
R
S
V
S
M
G
C
S
L
P
E
I
V
Baker's Yeast
Sacchar. cerevisiae
Q03529
384
44863
A216
V
V
Y
H
M
G
V
A
L
K
N
M
N
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
97.5
81.4
N.A.
82.5
81.1
N.A.
N.A.
67.7
59.6
N.A.
N.A.
N.A.
32.2
35.2
N.A.
Protein Similarity:
100
80.3
98.9
91.6
N.A.
89.7
89.2
N.A.
N.A.
79
72.8
N.A.
N.A.
N.A.
50.8
52.6
N.A.
P-Site Identity:
100
0
86.6
66.6
N.A.
46.6
53.3
N.A.
N.A.
60
53.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
73.3
80
N.A.
N.A.
80
73.3
N.A.
N.A.
N.A.
20
20
N.A.
Percent
Protein Identity:
29.8
N.A.
N.A.
28.7
27.8
N.A.
Protein Similarity:
43.2
N.A.
N.A.
42.7
47.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
8
8
0
24
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
39
0
0
0
0
0
8
31
0
% E
% Phe:
62
0
8
47
0
0
0
0
8
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
8
8
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
8
0
8
0
8
0
8
0
0
16
8
0
8
8
0
% I
% Lys:
0
8
0
8
0
8
0
0
0
8
0
0
0
24
0
% K
% Leu:
8
0
8
8
0
0
0
0
8
16
8
16
0
8
24
% L
% Met:
0
0
0
0
8
0
8
8
0
8
8
24
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
16
8
47
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
16
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
31
54
16
16
24
8
0
39
8
0
8
8
0
39
% S
% Thr:
0
16
8
0
54
31
8
0
8
0
8
0
0
0
0
% T
% Val:
16
16
0
8
8
8
8
8
8
24
8
39
8
8
16
% V
% Trp:
0
8
0
0
8
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
0
0
8
0
0
8
0
62
0
8
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _