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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FA2H
All Species:
21.82
Human Site:
Y330
Identified Species:
40
UniProt:
Q7L5A8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5A8
NP_077282.3
372
42791
Y330
P
H
K
G
S
Y
L
Y
S
L
K
A
H
H
V
Chimpanzee
Pan troglodytes
XP_511106
332
38028
S291
W
Q
L
R
V
L
R
S
L
L
G
V
W
L
W
Rhesus Macaque
Macaca mulatta
XP_001108607
372
42764
Y330
P
H
R
G
S
Y
L
Y
N
L
K
A
H
H
V
Dog
Lupus familis
XP_853014
372
42728
Y330
P
H
K
G
S
Y
L
Y
H
M
K
A
H
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5MPP0
372
42963
Y330
P
H
K
G
S
Y
L
Y
N
M
K
A
H
H
V
Rat
Rattus norvegicus
Q2LAM0
372
42655
Y330
P
H
K
G
S
Y
L
Y
N
M
K
A
H
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414053
365
42262
Y323
P
K
E
G
T
Y
L
Y
G
L
K
A
Y
H
V
Frog
Xenopus laevis
NP_001082707
369
42797
A328
P
S
K
G
S
Y
L
A
W
L
K
S
Y
H
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122312
313
37178
K272
G
T
Y
L
Y
L
L
K
R
I
H
N
Y
H
H
Nematode Worm
Caenorhab. elegans
NP_492678
316
36308
R275
H
H
G
S
P
R
P
R
S
N
L
H
F
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330558
236
27174
K195
Q
P
A
N
D
V
P
K
N
L
K
K
Y
H
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181023
237
27404
N196
P
T
R
P
V
T
K
N
L
K
K
Y
H
L
N
Baker's Yeast
Sacchar. cerevisiae
Q03529
384
44863
L341
L
P
P
F
M
R
K
L
K
K
Y
H
L
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
97.5
81.4
N.A.
82.5
81.1
N.A.
N.A.
67.7
59.6
N.A.
N.A.
N.A.
32.2
35.2
N.A.
Protein Similarity:
100
80.3
98.9
91.6
N.A.
89.7
89.2
N.A.
N.A.
79
72.8
N.A.
N.A.
N.A.
50.8
52.6
N.A.
P-Site Identity:
100
6.6
86.6
80
N.A.
86.6
86.6
N.A.
N.A.
66.6
66.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
100
6.6
100
86.6
N.A.
100
100
N.A.
N.A.
86.6
80
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Percent
Protein Identity:
29.8
N.A.
N.A.
28.7
27.8
N.A.
Protein Similarity:
43.2
N.A.
N.A.
42.7
47.1
N.A.
P-Site Identity:
20
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
0
0
47
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
54
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
8
47
0
0
0
0
0
0
8
0
8
16
47
70
16
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
39
0
0
0
16
16
8
16
70
8
0
0
8
% K
% Leu:
8
0
8
8
0
16
62
8
16
47
8
0
8
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
24
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
0
0
8
31
8
0
8
0
0
8
% N
% Pro:
62
16
8
8
8
0
16
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
16
8
0
16
8
8
8
0
0
0
0
8
0
% R
% Ser:
0
8
0
8
47
0
0
8
16
0
0
8
0
0
0
% S
% Thr:
0
16
0
0
8
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
16
8
0
0
0
0
0
8
0
0
47
% V
% Trp:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% W
% Tyr:
0
0
8
0
8
54
0
47
0
0
8
8
31
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _