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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FA2H All Species: 26.36
Human Site: Y34 Identified Species: 48.33
UniProt: Q7L5A8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L5A8 NP_077282.3 372 42791 Y34 V R R G A R L Y D L S S F V R
Chimpanzee Pan troglodytes XP_511106 332 38028 W26 R L A A G A C W V R R G A R L
Rhesus Macaque Macaca mulatta XP_001108607 372 42764 Y34 V R R G A R L Y D L S S F V R
Dog Lupus familis XP_853014 372 42728 Y34 V R C G A R L Y D L T G F L R
Cat Felis silvestris
Mouse Mus musculus Q5MPP0 372 42963 Y34 V R R G A S L Y D L T S F V R
Rat Rattus norvegicus Q2LAM0 372 42655 Y34 V R R G A S L Y D L T G F V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414053 365 42262 Y30 V R C R R R L Y D L S A F V R
Frog Xenopus laevis NP_001082707 369 42797 Y29 V L V G N K V Y D V S A F V N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122312 313 37178
Nematode Worm Caenorhab. elegans NP_492678 316 36308 P10 I G A D E K K P L L V Q L D G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330558 236 27174
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_181023 237 27404
Baker's Yeast Sacchar. cerevisiae Q03529 384 44863 Y36 T Y Q N R K I Y D V T R F L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.1 97.5 81.4 N.A. 82.5 81.1 N.A. N.A. 67.7 59.6 N.A. N.A. N.A. 32.2 35.2 N.A.
Protein Similarity: 100 80.3 98.9 91.6 N.A. 89.7 89.2 N.A. N.A. 79 72.8 N.A. N.A. N.A. 50.8 52.6 N.A.
P-Site Identity: 100 0 100 73.3 N.A. 86.6 80 N.A. N.A. 73.3 46.6 N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 100 6.6 100 86.6 N.A. 93.3 86.6 N.A. N.A. 80 73.3 N.A. N.A. N.A. 0 20 N.A.
Percent
Protein Identity: 29.8 N.A. N.A. 28.7 27.8 N.A.
Protein Similarity: 43.2 N.A. N.A. 42.7 47.1 N.A.
P-Site Identity: 0 N.A. N.A. 0 20 N.A.
P-Site Similarity: 0 N.A. N.A. 0 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 39 8 0 0 0 0 0 16 8 0 0 % A
% Cys: 0 0 16 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 62 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 62 0 0 % F
% Gly: 0 8 0 47 8 0 0 0 0 0 0 24 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 24 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 0 0 0 0 47 0 8 54 0 0 8 16 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 47 31 8 16 31 0 0 0 8 8 8 0 8 47 % R
% Ser: 0 0 0 0 0 16 0 0 0 0 31 24 0 0 8 % S
% Thr: 8 0 0 0 0 0 0 0 0 0 31 0 0 0 0 % T
% Val: 54 0 8 0 0 0 8 0 8 16 8 0 0 47 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _