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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FA2H
All Species:
13.33
Human Site:
Y357
Identified Species:
24.44
UniProt:
Q7L5A8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5A8
NP_077282.3
372
42791
Y357
I
S
T
K
L
W
D
Y
C
F
H
T
L
T
P
Chimpanzee
Pan troglodytes
XP_511106
332
38028
C318
S
T
K
L
W
D
Y
C
F
H
T
L
T
P
E
Rhesus Macaque
Macaca mulatta
XP_001108607
372
42764
Y357
I
S
T
K
L
W
D
Y
C
F
H
T
L
I
P
Dog
Lupus familis
XP_853014
372
42728
H357
I
S
S
K
L
W
D
H
F
F
H
T
L
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5MPP0
372
42963
Y357
I
S
T
K
L
W
D
Y
F
F
H
T
L
I
P
Rat
Rattus norvegicus
Q2LAM0
372
42655
Y357
I
S
T
K
L
W
D
Y
F
F
H
T
L
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414053
365
42262
H350
I
T
T
R
F
W
D
H
P
F
R
T
L
I
P
Frog
Xenopus laevis
NP_001082707
369
42797
R355
I
T
S
T
L
W
D
R
P
F
N
T
L
I
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122312
313
37178
G299
K
L
W
D
C
V
F
G
T
T
I
C
L
R
K
Nematode Worm
Caenorhab. elegans
NP_492678
316
36308
S302
V
G
F
G
I
S
T
S
L
W
D
Y
V
F
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330558
236
27174
R222
I
T
S
S
L
W
D
R
V
F
G
T
L
P
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181023
237
27404
V223
T
S
S
L
W
D
I
V
F
G
T
L
P
T
T
Baker's Yeast
Sacchar. cerevisiae
Q03529
384
44863
F368
S
W
F
W
D
E
V
F
G
T
Y
L
G
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
97.5
81.4
N.A.
82.5
81.1
N.A.
N.A.
67.7
59.6
N.A.
N.A.
N.A.
32.2
35.2
N.A.
Protein Similarity:
100
80.3
98.9
91.6
N.A.
89.7
89.2
N.A.
N.A.
79
72.8
N.A.
N.A.
N.A.
50.8
52.6
N.A.
P-Site Identity:
100
0
93.3
73.3
N.A.
86.6
86.6
N.A.
N.A.
53.3
53.3
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
6.6
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
73.3
73.3
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Percent
Protein Identity:
29.8
N.A.
N.A.
28.7
27.8
N.A.
Protein Similarity:
43.2
N.A.
N.A.
42.7
47.1
N.A.
P-Site Identity:
53.3
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
8
16
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
8
16
62
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
16
0
8
0
8
8
39
62
0
0
0
8
0
% F
% Gly:
0
8
0
8
0
0
0
8
8
8
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
8
39
0
0
0
8
% H
% Ile:
62
0
0
0
8
0
8
0
0
0
8
0
0
47
0
% I
% Lys:
8
0
8
39
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
16
54
0
0
0
8
0
0
24
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
0
0
8
24
62
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
16
0
0
8
0
0
8
0
% R
% Ser:
16
47
31
8
0
8
0
8
0
0
0
0
0
0
0
% S
% Thr:
8
31
39
8
0
0
8
0
8
16
16
62
8
16
8
% T
% Val:
8
0
0
0
0
8
8
8
8
0
0
0
8
0
0
% V
% Trp:
0
8
8
8
16
62
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
31
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _