KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FA2H
All Species:
25.45
Human Site:
Y81
Identified Species:
46.67
UniProt:
Q7L5A8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5A8
NP_077282.3
372
42791
Y81
R
R
W
L
E
Q
Y
Y
V
G
E
L
R
G
E
Chimpanzee
Pan troglodytes
XP_511106
332
38028
H67
A
D
L
D
G
P
P
H
R
H
S
A
N
A
R
Rhesus Macaque
Macaca mulatta
XP_001108607
372
42764
Y81
R
R
W
L
E
Q
Y
Y
V
G
E
L
R
G
E
Dog
Lupus familis
XP_853014
372
42728
Y81
R
L
W
L
E
Q
Y
Y
V
G
D
L
Q
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5MPP0
372
42963
Y81
R
R
W
L
E
Q
Y
Y
V
G
E
L
R
A
D
Rat
Rattus norvegicus
Q2LAM0
372
42655
Y81
R
R
W
L
E
Q
Y
Y
V
G
E
L
R
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414053
365
42262
Y77
R
R
W
L
E
Q
Y
Y
V
G
E
L
R
D
E
Frog
Xenopus laevis
NP_001082707
369
42797
Y76
R
R
W
L
E
Q
Y
Y
V
G
E
L
E
P
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122312
313
37178
G48
F
L
R
Y
H
P
G
G
K
K
I
L
S
Y
Y
Nematode Worm
Caenorhab. elegans
NP_492678
316
36308
E51
I
G
E
F
I
R
G
E
K
R
I
M
G
V
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330558
236
27174
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181023
237
27404
Baker's Yeast
Sacchar. cerevisiae
Q03529
384
44863
H104
R
L
L
T
N
K
N
H
K
V
E
V
Q
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
97.5
81.4
N.A.
82.5
81.1
N.A.
N.A.
67.7
59.6
N.A.
N.A.
N.A.
32.2
35.2
N.A.
Protein Similarity:
100
80.3
98.9
91.6
N.A.
89.7
89.2
N.A.
N.A.
79
72.8
N.A.
N.A.
N.A.
50.8
52.6
N.A.
P-Site Identity:
100
0
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
80
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Percent
Protein Identity:
29.8
N.A.
N.A.
28.7
27.8
N.A.
Protein Similarity:
43.2
N.A.
N.A.
42.7
47.1
N.A.
P-Site Identity:
0
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
8
0
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
8
0
0
8
24
% D
% Glu:
0
0
8
0
54
0
0
8
0
0
54
0
8
0
24
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
16
8
0
54
0
0
8
24
0
% G
% His:
0
0
0
0
8
0
0
16
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
16
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
24
8
0
0
0
0
0
% K
% Leu:
0
24
16
54
0
0
0
0
0
0
0
62
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
16
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
54
0
0
0
0
0
0
16
0
8
% Q
% Arg:
62
47
8
0
0
8
0
0
8
8
0
0
39
0
16
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
54
8
0
8
0
8
0
% V
% Trp:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
54
54
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _