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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPS6 All Species: 9.09
Human Site: S60 Identified Species: 20
UniProt: Q7L5N1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L5N1 NP_006824.2 327 36163 S60 D H W I R M R S Q E G R P V Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100125 326 36044 S59 D H W I R M R S Q E G R P V Q
Dog Lupus familis XP_536866 321 35704 R58 R M R S Q E G R P M Q V I G A
Cat Felis silvestris
Mouse Mus musculus O88545 324 35862 S57 D H W I R M R S Q E G R P M Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NUC2 318 35518 V59 Q E G R P M Q V I G A L I G K
Zebra Danio Brachydanio rerio NP_001017768 297 33615 E52 K Q E G R N I E V M N S F E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCY3 341 38287 A73 E H W T R F R A Q H G E P R Q
Honey Bee Apis mellifera XP_393678 338 37998 A70 E H W T R L R A Q E G T D Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192086 297 33638 E52 K Q E G R N I E V L N S F E L
Poplar Tree Populus trichocarpa XP_002330530 306 34249 R58 V I G V Q R G R T V E I F N S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W206 317 35640 R57 A M F Q Q N P R V Y G C V I G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99 97.5 N.A. 97.8 N.A. N.A. N.A. N.A. 88.6 83.7 N.A. 56.8 62.7 N.A. 70
Protein Similarity: 100 N.A. 99 97.8 N.A. 98.4 N.A. N.A. N.A. N.A. 93.8 87.7 N.A. 75 76.3 N.A. 80.7
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 N.A. N.A. N.A. N.A. 6.6 6.6 N.A. 53.3 46.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 N.A. N.A. N.A. N.A. 20 6.6 N.A. 66.6 66.6 N.A. 6.6
Percent
Protein Identity: 35.4 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 56.8 N.A. N.A. 56.5 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 19 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 28 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 19 10 19 0 0 10 0 19 0 37 10 10 0 19 0 % E
% Phe: 0 0 10 0 0 10 0 0 0 0 0 0 28 0 0 % F
% Gly: 0 0 19 19 0 0 19 0 0 10 55 0 0 19 10 % G
% His: 0 46 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 10 0 28 0 0 19 0 10 0 0 10 19 10 0 % I
% Lys: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 10 0 0 0 10 0 10 0 0 28 % L
% Met: 0 19 0 0 0 37 0 0 0 19 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 28 0 0 0 0 19 0 0 10 0 % N
% Pro: 0 0 0 0 10 0 10 0 10 0 0 0 37 0 0 % P
% Gln: 10 19 0 10 28 0 10 0 46 0 10 0 0 10 37 % Q
% Arg: 10 0 10 10 64 10 46 28 0 0 0 28 0 10 0 % R
% Ser: 0 0 0 10 0 0 0 28 0 0 0 19 0 0 10 % S
% Thr: 0 0 0 19 0 0 0 0 10 0 0 10 0 0 0 % T
% Val: 10 0 0 10 0 0 0 10 28 10 0 10 10 19 0 % V
% Trp: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _