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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS6
All Species:
20.61
Human Site:
Y125
Identified Species:
45.33
UniProt:
Q7L5N1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5N1
NP_006824.2
327
36163
Y125
E
L
E
F
L
G
W
Y
T
T
G
G
P
P
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100125
326
36044
Y124
E
L
E
F
L
G
W
Y
T
T
G
G
P
P
D
Dog
Lupus familis
XP_536866
321
35704
Y119
E
L
E
F
L
G
W
Y
T
T
G
G
P
P
D
Cat
Felis silvestris
Mouse
Mus musculus
O88545
324
35862
Y122
E
L
E
F
L
G
W
Y
T
T
G
G
P
P
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NUC2
318
35518
Y116
D
M
E
F
L
G
W
Y
T
T
G
G
T
P
D
Zebra Danio
Brachydanio rerio
NP_001017768
297
33615
Q103
T
T
G
G
S
P
D
Q
S
D
I
H
I
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCY3
341
38287
T139
L
D
F
I
G
W
Y
T
T
G
D
N
P
T
A
Honey Bee
Apis mellifera
XP_393678
338
37998
T136
M
D
F
L
G
W
Y
T
T
G
D
M
P
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192086
297
33638
E103
T
T
G
G
S
P
D
E
S
D
I
K
V
H
K
Poplar Tree
Populus trichocarpa
XP_002330530
306
34249
E109
Y
S
T
G
S
D
A
E
E
S
D
M
H
I
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W206
317
35640
T115
Y
I
L
G
W
Y
S
T
G
S
D
A
E
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
97.5
N.A.
97.8
N.A.
N.A.
N.A.
N.A.
88.6
83.7
N.A.
56.8
62.7
N.A.
70
Protein Similarity:
100
N.A.
99
97.8
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
93.8
87.7
N.A.
75
76.3
N.A.
80.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
80
0
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
6.6
N.A.
20
26.6
N.A.
6.6
Percent
Protein Identity:
35.4
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
56.8
N.A.
N.A.
56.5
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
0
0
0
10
19
0
0
19
37
0
0
0
46
% D
% Glu:
37
0
46
0
0
0
0
19
10
0
0
0
10
10
10
% E
% Phe:
0
0
19
46
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
19
37
19
46
0
0
10
19
46
46
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
19
10
% H
% Ile:
0
10
0
10
0
0
0
0
0
0
19
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
19
% K
% Leu:
10
37
10
10
46
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
19
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
19
0
0
0
0
0
0
55
46
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
28
0
10
0
19
19
0
0
0
0
10
% S
% Thr:
19
19
10
0
0
0
0
28
64
46
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
10
19
46
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
10
19
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _