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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DET1
All Species:
27.27
Human Site:
S467
Identified Species:
54.55
UniProt:
Q7L5Y6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5Y6
NP_001137546.1
550
63848
S467
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Chimpanzee
Pan troglodytes
XP_001164700
516
59763
W438
L
F
S
Y
D
D
K
W
V
S
V
M
E
R
P
Rhesus Macaque
Macaca mulatta
XP_001089083
561
65069
S478
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Dog
Lupus familis
XP_536186
811
91626
S728
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0A0
550
63819
S467
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413870
551
63959
S468
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955964
563
65339
S480
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623769
555
64215
C474
Y
L
D
L
S
L
F
C
Y
D
D
K
W
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795871
570
66247
S486
Y
L
D
L
S
L
F
S
Y
D
D
K
W
V
S
Poplar Tree
Populus trichocarpa
XP_002319992
530
61269
R448
Y
F
D
Q
S
L
F
R
Y
D
E
K
L
I
S
Maize
Zea mays
NP_001147932
509
59167
E431
L
S
L
F
R
Y
D
E
K
L
I
S
A
I
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48732
543
62473
R460
Y
F
D
Q
S
L
F
R
F
D
E
K
L
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
97.8
67.3
N.A.
99.6
N.A.
N.A.
N.A.
96.3
N.A.
86.8
N.A.
N.A.
62.1
N.A.
70.8
Protein Similarity:
100
91.4
98
67.6
N.A.
100
N.A.
N.A.
N.A.
98.7
N.A.
92.3
N.A.
N.A.
76
N.A.
79.8
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
93.3
N.A.
100
P-Site Similarity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
93.3
N.A.
100
Percent
Protein Identity:
33.2
30
N.A.
31.6
N.A.
N.A.
Protein Similarity:
53.8
51.6
N.A.
52.3
N.A.
N.A.
P-Site Identity:
60
0
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
73.3
6.6
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
84
0
9
9
9
0
0
84
67
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
17
0
9
0
0
% E
% Phe:
0
25
0
9
0
0
84
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
25
0
% I
% Lys:
0
0
0
0
0
0
9
0
9
0
0
84
0
0
0
% K
% Leu:
17
67
9
67
0
84
0
0
0
9
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
17
0
0
0
0
0
9
0
% R
% Ser:
0
9
9
0
84
0
0
59
0
9
0
9
0
0
84
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
9
0
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
67
0
0
% W
% Tyr:
84
0
0
9
0
9
0
0
75
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _