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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAEA All Species: 39.7
Human Site: S343 Identified Species: 67.18
UniProt: Q7L5Y9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L5Y9 NP_001017405.1 396 45287 S343 S R L V C K I S G D V M N E N
Chimpanzee Pan troglodytes XP_517061 396 45239 S343 S R L V C K I S G D V M N E N
Rhesus Macaque Macaca mulatta XP_001092058 403 46024 S350 S R L V C K I S G D V M N E N
Dog Lupus familis XP_853384 488 55272 S435 S R L V C K I S G D V M N E N
Cat Felis silvestris
Mouse Mus musculus Q4VC33 396 45318 S343 S R L V C K I S G D V M N E N
Rat Rattus norvegicus NP_001008320 385 44202 S332 S R L V C K I S G D V M N E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F398 396 45370 S343 S R L V C K I S G D V M N E N
Frog Xenopus laevis Q6GR10 396 45462 S343 S R L V C K I S G D V M N E N
Zebra Danio Brachydanio rerio Q7SXR3 396 45324 S343 S R L V C K I S G E V M N E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733044 394 45357 G341 R L I C R V T G L P L N E H N
Honey Bee Apis mellifera XP_395151 353 40572 N303 S I S G K P L N E Y N Q P M M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202321 330 37717 M279 C S L S G H V M N E H N P P M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40492 516 59876 T440 N C P V C S E T F K P I T Q A
Red Bread Mold Neurospora crassa Q7S2X0 410 46453 S355 N V P Y A H H S K S H L D N D
Conservation
Percent
Protein Identity: 100 99.7 98.2 78.2 N.A. 98.7 95.9 N.A. N.A. 96.7 94.9 93.6 N.A. 47.9 51.2 N.A. 48.7
Protein Similarity: 100 99.7 98.2 79 N.A. 99.4 96.7 N.A. N.A. 98.9 97.7 97.4 N.A. 66.6 66.1 N.A. 63.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 20 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 30.9
Protein Similarity: N.A. N.A. N.A. N.A. 42.2 49.7
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 8 8 0 8 72 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 58 0 0 8 0 8 % D
% Glu: 0 0 0 0 0 0 8 0 8 15 0 0 8 65 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 8 0 0 8 65 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 15 8 0 0 0 15 0 0 8 0 % H
% Ile: 0 8 8 0 0 0 65 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 8 65 0 0 8 8 0 0 0 0 0 % K
% Leu: 0 8 72 0 0 0 8 0 8 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 65 0 8 15 % M
% Asn: 15 0 0 0 0 0 0 8 8 0 8 15 65 8 72 % N
% Pro: 0 0 15 0 0 8 0 0 0 8 8 0 15 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 8 65 0 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 72 8 8 8 0 8 0 72 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % T
% Val: 0 8 0 72 0 8 8 0 0 0 65 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _