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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPM2AIP1
All Species:
22.12
Human Site:
Y460
Identified Species:
69.52
UniProt:
Q7L775
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L775
NP_055620.1
607
70370
Y460
K
I
F
D
P
D
R
Y
Q
M
V
I
C
R
L
Chimpanzee
Pan troglodytes
XP_526480
607
70348
Y460
K
I
F
D
P
D
R
Y
Q
M
V
I
C
R
L
Rhesus Macaque
Macaca mulatta
XP_001090676
607
70206
Y460
K
I
F
D
P
D
R
Y
Q
M
V
I
C
R
L
Dog
Lupus familis
XP_851144
608
70213
Y461
K
I
F
D
P
D
R
Y
Q
V
V
I
C
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEH5
606
70078
Y461
K
I
F
D
P
D
R
Y
Q
M
V
I
S
R
L
Rat
Rattus norvegicus
XP_002727186
640
73625
Y461
K
I
F
D
P
D
R
Y
Q
M
V
I
S
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664076
616
71120
F477
E
Q
S
F
E
E
R
F
S
K
L
R
Q
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107668
618
70437
D471
Q
D
Y
V
A
S
I
D
R
L
I
E
Q
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
91.1
N.A.
88.9
84.3
N.A.
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
100
98.6
96.5
N.A.
95.3
90.7
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% C
% Asp:
0
13
0
75
0
75
0
13
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
13
13
0
0
0
0
0
13
0
0
0
% E
% Phe:
0
0
75
13
0
0
0
13
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
75
0
0
0
0
13
0
0
0
13
75
0
0
0
% I
% Lys:
75
0
0
0
0
0
0
0
0
13
0
0
0
13
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
13
13
0
0
0
75
% L
% Met:
0
0
0
0
0
0
0
0
0
63
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
13
0
0
0
0
0
0
75
0
0
0
25
0
0
% Q
% Arg:
0
0
0
0
0
0
88
0
13
0
0
13
0
75
13
% R
% Ser:
0
0
13
0
0
13
0
0
13
0
0
0
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% T
% Val:
0
0
0
13
0
0
0
0
0
13
75
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _