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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT13
All Species:
21.52
Human Site:
S185
Identified Species:
43.03
UniProt:
Q7L8C5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L8C5
NP_065877.1
426
46885
S185
T
R
L
E
A
V
T
S
N
H
D
G
G
C
D
Chimpanzee
Pan troglodytes
XP_521898
426
46852
S185
T
R
L
E
A
V
T
S
N
H
D
G
G
C
D
Rhesus Macaque
Macaca mulatta
XP_001104396
603
64583
S362
T
S
L
E
A
V
T
S
N
H
D
G
G
C
D
Dog
Lupus familis
XP_540764
465
51160
S224
T
R
L
E
A
V
T
S
G
H
D
G
G
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQT6
426
46851
S185
T
S
L
E
A
V
T
S
D
H
E
G
G
C
D
Rat
Rattus norvegicus
Q925B5
426
46862
S185
T
S
L
E
A
V
T
S
D
H
E
G
G
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518732
383
42070
R172
A
Q
T
V
L
K
K
R
L
P
R
T
A
W
E
Chicken
Gallus gallus
P47191
424
47487
A173
I
Q
A
A
E
L
P
A
L
D
M
G
G
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017652
420
46040
V178
V
E
A
E
N
I
S
V
E
A
G
C
E
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
L219
T
V
I
Q
A
E
E
L
P
A
L
D
M
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34693
441
49885
G188
I
Q
A
E
D
L
P
G
M
D
M
S
G
T
S
Sea Urchin
Strong. purpuratus
XP_795813
248
28111
Q38
K
I
K
Q
S
V
V
Q
R
R
T
L
N
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
69.6
84.3
N.A.
89.9
89.9
N.A.
70.8
25.1
N.A.
44.8
N.A.
23
N.A.
23.5
23.2
Protein Similarity:
100
100
69.9
87
N.A.
94.3
94.1
N.A.
76.7
44.1
N.A.
62.4
N.A.
41.3
N.A.
41.9
36.8
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
0
13.3
N.A.
6.6
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
33.3
N.A.
20
N.A.
26.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
9
59
0
0
9
0
17
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
50
0
% C
% Asp:
0
0
0
0
9
0
0
0
17
17
34
9
0
0
50
% D
% Glu:
0
9
0
67
9
9
9
0
9
0
17
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
9
0
9
59
67
17
9
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
17
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
50
0
9
17
0
9
17
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
17
0
9
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
25
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
17
0
9
9
0
0
0
9
0
% P
% Gln:
0
25
0
17
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
25
0
0
0
0
0
9
9
9
9
0
0
0
0
% R
% Ser:
0
25
0
0
9
0
9
50
0
0
0
9
0
0
17
% S
% Thr:
59
0
9
0
0
0
50
0
0
0
9
9
0
17
0
% T
% Val:
9
9
0
9
0
59
9
9
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _