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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3BP5L
All Species:
17.58
Human Site:
S49
Identified Species:
55.24
UniProt:
Q7L8J4
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L8J4
NP_085148.1
393
43499
S49
S
S
S
E
A
K
L
S
P
R
E
E
E
E
L
Chimpanzee
Pan troglodytes
XP_514329
393
43490
S49
S
S
S
E
A
K
L
S
P
R
E
E
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001107738
393
43463
S49
S
S
S
E
A
K
L
S
P
R
E
E
E
E
L
Dog
Lupus familis
XP_859988
393
43523
S49
G
S
T
E
A
K
L
S
P
R
E
E
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH9
392
43356
S49
N
S
S
E
T
K
L
S
P
R
E
E
E
E
L
Rat
Rattus norvegicus
Q91Y80
457
50810
E42
Q
G
L
E
E
E
E
E
V
D
P
R
I
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U584
373
41573
E54
D
A
K
K
E
E
I
E
E
E
L
D
P
R
I
Zebra Danio
Brachydanio rerio
XP_687006
465
52948
A58
S
K
T
D
N
T
E
A
V
E
K
D
K
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.2
93.3
N.A.
94.6
34.1
N.A.
N.A.
N.A.
63.8
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.4
94.6
N.A.
96.1
51.2
N.A.
N.A.
N.A.
72
65.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
N.A.
N.A.
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
50
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
13
0
0
0
0
0
13
0
25
0
0
0
% D
% Glu:
0
0
0
75
25
25
25
25
13
25
63
63
63
63
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
13
% I
% Lys:
0
13
13
13
0
63
0
0
0
0
13
0
13
0
0
% K
% Leu:
0
0
13
0
0
0
63
0
0
0
13
0
0
0
63
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
63
0
13
0
13
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
63
0
13
0
13
0
% R
% Ser:
50
63
50
0
0
0
0
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
25
0
13
13
0
0
0
0
0
0
0
13
0
% T
% Val:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _