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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTUD6A All Species: 29.39
Human Site: Y269 Identified Species: 58.79
UniProt: Q7L8S5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L8S5 NP_997203.1 288 33300 Y269 A Y S L G E H Y N S V T P L E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082689 288 33355 Y269 A Y S L G E H Y N S V R P L E
Dog Lupus familis XP_549057 311 35778 Y292 A C N L G E H Y N S V K P L E
Cat Felis silvestris
Mouse Mus musculus Q6IE21 290 33720 Y270 A C D F G E H Y N S V K P I E
Rat Rattus norvegicus NP_001100109 324 37090 Y309 A Y G L G E H Y N S V T R L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIP6 302 34523 Y287 A Y G L G E H Y N S V K L L T
Frog Xenopus laevis Q6GM06 294 33413 Y281 A Y G L G E H Y N S V E Q L D
Zebra Danio Brachydanio rerio Q7ZV00 293 33488 Y278 A Y G L G E H Y N S V E P L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648769 312 35234 Q300 C Y H R H I Y Q L G A H Y N S
Honey Bee Apis mellifera XP_623906 297 34672 H284 H M Y E L G A H Y N S V T K Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795260 291 33248 Y276 A Y G L G E H Y N S V M E R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38747 307 36094 E279 R P I Q V Y N E C G K N P E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.3 65.5 N.A. 63.4 47.5 N.A. N.A. 49.3 47.2 46.4 N.A. 36.8 39 N.A. 37.4
Protein Similarity: 100 N.A. 95.8 80.3 N.A. 80 68.2 N.A. N.A. 69.8 70.4 70.9 N.A. 59.9 60.9 N.A. 62.8
P-Site Identity: 100 N.A. 93.3 80 N.A. 66.6 80 N.A. N.A. 73.3 73.3 80 N.A. 6.6 0 N.A. 73.3
P-Site Similarity: 100 N.A. 93.3 86.6 N.A. 73.3 80 N.A. N.A. 73.3 80 86.6 N.A. 13.3 13.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 75 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % A
% Cys: 9 17 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 9 0 75 0 9 0 0 0 17 9 9 42 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 42 0 75 9 0 0 0 17 0 0 0 0 0 % G
% His: 9 0 9 0 9 0 75 9 0 0 0 9 0 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 25 0 9 9 % K
% Leu: 0 0 0 67 9 0 0 0 9 0 0 0 9 59 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 0 0 9 0 75 9 0 9 0 9 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 50 0 0 % P
% Gln: 0 0 0 9 0 0 0 9 0 0 0 0 9 0 0 % Q
% Arg: 9 0 0 9 0 0 0 0 0 0 0 9 9 9 0 % R
% Ser: 0 0 17 0 0 0 0 0 0 75 9 0 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 17 9 0 9 % T
% Val: 0 0 0 0 9 0 0 0 0 0 75 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 67 9 0 0 9 9 75 9 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _