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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRP2 All Species: 36.06
Human Site: S253 Identified Species: 88.15
UniProt: Q7LDG7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7LDG7 NP_001092140.1 609 69248 S253 V V G G L S H S S I S R L K E
Chimpanzee Pan troglodytes XP_508531 671 75529 S315 V V G G L S H S S I S R L K E
Rhesus Macaque Macaca mulatta XP_001118242 840 93530 S484 V V G G L S H S S I S R L K E
Dog Lupus familis XP_854922 606 68799 S253 V V G G L S H S S I S R L K E
Cat Felis silvestris
Mouse Mus musculus Q9QUG9 608 69427 S253 V V G G L S H S S I S R L K E
Rat Rattus norvegicus P0C643 608 69273 S253 V V G G L S H S S I S R L K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519551 554 63139 A230 S L T E L V T A T G N Y G N Y
Chicken Gallus gallus NP_001006401 691 78529 S251 V V G G L S H S S I S R L K E
Frog Xenopus laevis Q6DCK3 594 68320 S248 V V G G L S H S S I S R L K D
Zebra Danio Brachydanio rerio XP_685135 602 68890 S247 V V G G L S N S S I A R L K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 72.3 97.3 N.A. 96.2 96.8 N.A. 77 47.7 64.1 58.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.4 72.3 98.3 N.A. 97.8 98 N.A. 81.6 62 78.1 74.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 93.3 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 100 100 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 70 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 90 90 0 0 0 0 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 90 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 % K
% Leu: 0 10 0 0 100 0 0 0 0 0 0 0 90 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 10 0 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 % R
% Ser: 10 0 0 0 0 90 0 90 90 0 80 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 10 0 10 0 0 0 0 0 0 % T
% Val: 90 90 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _