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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM2B
All Species:
4.55
Human Site:
S18
Identified Species:
7.69
UniProt:
Q7LG56
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7LG56
NP_056528.2
351
40737
S18
G
L
D
Q
D
E
R
S
S
S
D
T
N
E
S
Chimpanzee
Pan troglodytes
XP_001153859
297
34470
Rhesus Macaque
Macaca mulatta
XP_001099964
297
34498
Dog
Lupus familis
XP_539109
351
40882
L18
R
P
E
P
D
E
R
L
S
S
D
T
N
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6PEE3
351
40785
L18
R
P
E
K
G
E
Q
L
C
S
E
T
E
E
N
Rat
Rattus norvegicus
Q4KLN6
390
45020
E57
R
I
F
Q
D
S
A
E
L
E
S
K
A
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508783
401
45907
F68
R
E
S
R
G
G
D
F
S
S
E
P
T
E
N
Chicken
Gallus gallus
XP_418364
353
40764
S20
A
A
G
P
E
R
S
S
S
P
S
A
A
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P79733
386
44575
S53
A
R
K
I
F
D
E
S
E
G
Q
S
K
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48592
393
45096
S60
G
I
G
K
S
A
N
S
L
M
E
K
S
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42170
381
44271
E48
T
K
A
A
S
A
E
E
T
N
N
E
S
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6Y657
333
38312
I9
P
S
M
P
E
E
P
I
L
T
P
T
P
D
R
Baker's Yeast
Sacchar. cerevisiae
P09938
399
46129
Q63
K
A
Y
L
K
S
H
Q
V
H
R
H
K
L
K
Red Bread Mold
Neurospora crassa
Q9C167
410
46679
K64
N
K
K
A
A
E
A
K
K
M
A
P
T
L
K
Conservation
Percent
Protein Identity:
100
84.6
83.7
95.7
N.A.
93.4
70.2
N.A.
79
87.5
N.A.
71.5
N.A.
67.1
N.A.
61.6
N.A.
Protein Similarity:
100
84.6
84.6
98.5
N.A.
97.4
82
N.A.
84.7
92.6
N.A.
81.8
N.A.
77.6
N.A.
76.1
N.A.
P-Site Identity:
100
0
0
60
N.A.
26.6
13.3
N.A.
20
20
N.A.
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
0
0
73.3
N.A.
60
26.6
N.A.
40
33.3
N.A.
20
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.8
56.8
61.2
Protein Similarity:
N.A.
N.A.
N.A.
74.6
73.1
74.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
8
15
8
15
15
0
0
0
8
8
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
22
8
8
0
0
0
15
0
0
8
0
% D
% Glu:
0
8
15
0
15
36
15
15
8
8
22
8
8
43
0
% E
% Phe:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
15
0
15
0
15
8
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% H
% Ile:
0
15
0
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
15
15
15
8
0
0
8
8
0
0
15
15
0
22
% K
% Leu:
0
8
0
8
0
0
0
15
22
0
0
0
0
15
0
% L
% Met:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
8
8
0
15
0
29
% N
% Pro:
8
15
0
22
0
0
8
0
0
8
8
15
8
8
0
% P
% Gln:
0
0
0
15
0
0
8
8
0
0
8
0
0
0
0
% Q
% Arg:
29
8
0
8
0
8
15
0
0
0
8
0
0
0
8
% R
% Ser:
0
8
8
0
15
15
8
29
29
29
15
8
15
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
8
8
0
29
15
0
15
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _