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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM2B
All Species:
40
Human Site:
S225
Identified Species:
67.69
UniProt:
Q7LG56
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7LG56
NP_056528.2
351
40737
S225
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Chimpanzee
Pan troglodytes
XP_001153859
297
34470
C182
G
L
H
C
D
F
A
C
L
M
F
Q
Y
L
V
Rhesus Macaque
Macaca mulatta
XP_001099964
297
34498
C182
G
L
H
C
D
F
A
C
L
M
F
Q
Y
L
V
Dog
Lupus familis
XP_539109
351
40882
S225
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6PEE3
351
40785
S225
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Rat
Rattus norvegicus
Q4KLN6
390
45020
S264
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508783
401
45907
S275
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Chicken
Gallus gallus
XP_418364
353
40764
S227
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P79733
386
44575
S260
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48592
393
45096
S267
T
F
S
N
E
L
I
S
R
D
E
G
L
H
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42170
381
44271
S255
T
H
S
N
E
L
I
S
R
D
E
G
L
H
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6Y657
333
38312
F209
D
E
G
L
H
C
D
F
A
C
L
I
Y
S
L
Baker's Yeast
Sacchar. cerevisiae
P09938
399
46129
C270
T
F
S
N
E
L
I
C
R
D
E
G
L
H
T
Red Bread Mold
Neurospora crassa
Q9C167
410
46679
S271
T
F
S
N
E
L
I
S
R
D
E
G
L
H
T
Conservation
Percent
Protein Identity:
100
84.6
83.7
95.7
N.A.
93.4
70.2
N.A.
79
87.5
N.A.
71.5
N.A.
67.1
N.A.
61.6
N.A.
Protein Similarity:
100
84.6
84.6
98.5
N.A.
97.4
82
N.A.
84.7
92.6
N.A.
81.8
N.A.
77.6
N.A.
76.1
N.A.
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
N.A.
86.6
N.A.
P-Site Similarity:
100
6.6
6.6
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.8
56.8
61.2
Protein Similarity:
N.A.
N.A.
N.A.
74.6
73.1
74.3
P-Site Identity:
N.A.
N.A.
N.A.
0
86.6
93.3
P-Site Similarity:
N.A.
N.A.
N.A.
0
86.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
15
0
8
0
22
0
8
0
0
0
0
58
% C
% Asp:
8
0
0
0
15
0
8
0
0
79
0
0
0
0
0
% D
% Glu:
0
8
0
0
79
0
0
0
0
0
79
0
0
0
0
% E
% Phe:
0
72
0
0
0
15
0
8
0
0
15
0
0
0
0
% F
% Gly:
15
0
8
0
0
0
0
0
0
0
0
79
0
0
0
% G
% His:
0
8
15
0
8
0
0
0
0
0
0
0
0
79
0
% H
% Ile:
0
0
0
0
0
0
79
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
8
0
79
0
0
15
0
8
0
79
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
79
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
79
0
0
0
0
0
8
% R
% Ser:
0
0
79
0
0
0
0
72
0
0
0
0
0
8
0
% S
% Thr:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _