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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM2B
All Species:
43.03
Human Site:
Y145
Identified Species:
72.82
UniProt:
Q7LG56
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7LG56
NP_056528.2
351
40737
Y145
Y
S
L
L
I
D
T
Y
I
R
D
P
K
K
R
Chimpanzee
Pan troglodytes
XP_001153859
297
34470
P109
F
N
A
I
E
T
M
P
Y
V
K
K
K
A
D
Rhesus Macaque
Macaca mulatta
XP_001099964
297
34498
P109
F
N
A
I
E
T
M
P
Y
V
K
K
K
A
D
Dog
Lupus familis
XP_539109
351
40882
Y145
Y
S
L
L
I
D
T
Y
I
R
D
P
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PEE3
351
40785
Y145
Y
S
L
L
I
D
T
Y
I
R
D
P
K
K
R
Rat
Rattus norvegicus
Q4KLN6
390
45020
Y184
Y
S
L
L
I
D
T
Y
I
K
D
S
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508783
401
45907
Y195
Y
S
L
L
I
D
T
Y
I
K
D
P
K
K
R
Chicken
Gallus gallus
XP_418364
353
40764
Y147
Y
S
L
L
I
D
T
Y
I
K
D
P
E
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P79733
386
44575
Y180
Y
S
L
L
I
D
T
Y
I
K
D
S
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48592
393
45096
Y187
Y
S
V
L
I
D
T
Y
I
R
D
P
H
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42170
381
44271
Y175
Y
S
K
L
I
E
T
Y
I
R
D
E
T
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6Y657
333
38312
E136
D
H
L
F
R
A
I
E
T
I
P
C
V
T
K
Baker's Yeast
Sacchar. cerevisiae
P09938
399
46129
Y190
Y
S
L
L
I
D
T
Y
I
K
D
P
K
E
S
Red Bread Mold
Neurospora crassa
Q9C167
410
46679
Y191
Y
S
L
L
I
D
T
Y
I
K
E
P
S
Q
R
Conservation
Percent
Protein Identity:
100
84.6
83.7
95.7
N.A.
93.4
70.2
N.A.
79
87.5
N.A.
71.5
N.A.
67.1
N.A.
61.6
N.A.
Protein Similarity:
100
84.6
84.6
98.5
N.A.
97.4
82
N.A.
84.7
92.6
N.A.
81.8
N.A.
77.6
N.A.
76.1
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
80
N.A.
93.3
86.6
N.A.
80
N.A.
80
N.A.
66.6
N.A.
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
93.3
N.A.
100
100
N.A.
93.3
N.A.
93.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.8
56.8
61.2
Protein Similarity:
N.A.
N.A.
N.A.
74.6
73.1
74.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
80
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
8
0
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
72
0
0
0
0
72
0
0
0
15
% D
% Glu:
0
0
0
0
15
8
0
8
0
0
8
8
8
29
0
% E
% Phe:
15
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
15
79
0
8
0
79
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
43
15
15
65
36
8
% K
% Leu:
0
0
72
79
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
15
0
0
8
58
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
36
0
0
0
0
72
% R
% Ser:
0
79
0
0
0
0
0
0
0
0
0
15
8
0
8
% S
% Thr:
0
0
0
0
0
15
79
0
8
0
0
0
8
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
15
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
79
0
0
0
0
0
0
79
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _