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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HS2ST1
All Species:
44.55
Human Site:
Y159
Identified Species:
81.67
UniProt:
Q7LGA3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7LGA3
NP_001127964.1
356
41881
Y159
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109871
356
41849
Y159
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Dog
Lupus familis
XP_537087
349
41018
Y152
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3H7
356
41795
Y159
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Rat
Rattus norvegicus
NP_001093988
356
41833
Y159
G
V
K
K
K
P
I
Y
I
N
V
V
R
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506529
442
50613
Y245
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Chicken
Gallus gallus
Q76KB1
356
41683
Y159
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Frog
Xenopus laevis
O93336
356
41730
Y159
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Zebra Danio
Brachydanio rerio
NP_001074139
354
41716
Y157
G
V
K
K
K
P
I
Y
I
N
V
I
R
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25722
349
41254
Y158
Q
I
A
H
K
P
I
Y
I
N
L
V
R
K
P
Honey Bee
Apis mellifera
XP_623840
343
40647
Y151
G
I
K
Q
T
P
L
Y
I
N
L
L
R
K
P
Nematode Worm
Caenorhab. elegans
O17645
324
37906
I126
G
I
A
N
P
I
Y
I
N
I
I
R
E
P
L
Sea Urchin
Strong. purpuratus
XP_781906
196
22958
Y18
S
A
K
Q
P
G
F
Y
H
G
H
F
A
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.1
N.A.
97.4
97.4
N.A.
58.3
94
91
84.8
N.A.
51.9
47.4
42.7
30.6
Protein Similarity:
100
N.A.
100
97.4
N.A.
99.4
99.7
N.A.
65.3
98
96.3
94.3
N.A.
69.9
64.6
60.1
40.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
100
100
100
N.A.
53.3
53.3
6.6
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
86.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
85
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
24
0
0
0
8
77
8
85
8
8
62
0
0
8
% I
% Lys:
0
0
85
70
77
0
0
0
0
0
0
0
0
16
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
16
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
85
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
85
0
0
0
0
0
0
0
8
85
% P
% Gln:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
85
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
70
0
0
0
0
0
0
0
0
70
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
93
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _