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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HS2ST1
All Species:
35.76
Human Site:
Y242
Identified Species:
65.56
UniProt:
Q7LGA3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7LGA3
NP_001127964.1
356
41881
Y242
W
A
M
D
Q
A
K
Y
N
L
I
N
E
Y
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109871
356
41849
Y242
W
A
M
D
Q
A
K
Y
N
L
V
N
E
Y
F
Dog
Lupus familis
XP_537087
349
41018
Y235
W
A
M
D
Q
A
K
Y
N
L
I
N
E
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3H7
356
41795
S242
W
A
M
D
Q
A
K
S
N
L
I
N
E
Y
F
Rat
Rattus norvegicus
NP_001093988
356
41833
Y242
W
A
M
D
Q
A
K
Y
N
L
V
N
E
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506529
442
50613
Y328
W
A
M
D
Q
A
K
Y
N
L
I
N
E
Y
F
Chicken
Gallus gallus
Q76KB1
356
41683
Y242
W
A
L
E
Q
A
K
Y
N
L
I
N
E
Y
F
Frog
Xenopus laevis
O93336
356
41730
Y242
W
A
L
D
Q
A
K
Y
N
L
V
N
E
Y
F
Zebra Danio
Brachydanio rerio
NP_001074139
354
41716
Y240
W
A
L
E
Q
A
K
Y
N
L
V
N
E
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25722
349
41254
R241
W
A
L
D
Q
A
K
R
N
L
V
N
E
Y
F
Honey Bee
Apis mellifera
XP_623840
343
40647
R234
W
A
L
E
E
A
K
R
N
L
Q
K
H
Y
L
Nematode Worm
Caenorhab. elegans
O17645
324
37906
Q208
E
A
L
R
V
A
K
Q
N
V
L
E
K
Y
L
Sea Urchin
Strong. purpuratus
XP_781906
196
22958
M98
H
M
E
E
F
V
A
M
L
E
A
S
L
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
97.1
N.A.
97.4
97.4
N.A.
58.3
94
91
84.8
N.A.
51.9
47.4
42.7
30.6
Protein Similarity:
100
N.A.
100
97.4
N.A.
99.4
99.7
N.A.
65.3
98
96.3
94.3
N.A.
69.9
64.6
60.1
40.7
P-Site Identity:
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
100
86.6
86.6
73.3
N.A.
80
46.6
33.3
0
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
100
100
100
93.3
N.A.
93.3
66.6
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
93
0
0
0
93
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
31
8
0
0
0
0
8
0
8
77
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
70
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
93
0
0
0
0
8
8
0
0
% K
% Leu:
0
0
47
0
0
0
0
0
8
85
8
0
8
0
16
% L
% Met:
0
8
47
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
93
0
0
77
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
77
0
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
8
39
0
0
0
0
% V
% Trp:
85
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
93
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _