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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHF
All Species:
2.42
Human Site:
T106
Identified Species:
5.93
UniProt:
Q7M4L6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7M4L6
NP_612365
480
53297
T106
Q
P
H
S
W
M
L
T
P
S
P
L
N
S
H
Chimpanzee
Pan troglodytes
XP_001146974
435
47987
T78
F
E
N
T
E
C
T
T
V
L
G
T
T
I
S
Rhesus Macaque
Macaca mulatta
XP_001111408
422
46812
S65
H
R
E
P
R
S
S
S
P
P
P
V
A
N
G
Dog
Lupus familis
XP_544661
474
51622
R99
D
S
P
S
G
L
C
R
S
R
R
G
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG80
238
26875
Rat
Rattus norvegicus
XP_342508
481
52377
F101
R
L
Q
R
D
R
D
F
E
D
P
Y
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521547
300
33125
Chicken
Gallus gallus
XP_413725
381
42036
A24
A
S
D
G
P
V
A
A
G
E
S
P
T
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038542
391
44295
A33
T
E
S
E
I
L
K
A
Y
R
A
Q
K
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623264
1122
125495
Q258
Q
Q
Q
Q
L
Q
L
Q
Q
H
Q
L
Q
Q
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
83.5
70.2
N.A.
47.5
67.9
N.A.
52.2
55
N.A.
38.5
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
100
76
84.5
75.4
N.A.
48.5
73.1
N.A.
55
61.2
N.A.
51.8
N.A.
N.A.
29.9
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
6.6
N.A.
0
6.6
N.A.
0
0
N.A.
0
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
100
20
33.3
13.3
N.A.
0
20
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
20
0
0
10
0
20
0
10
% A
% Cys:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
0
10
0
0
10
0
0
0
0
10
% D
% Glu:
0
20
10
10
10
0
0
0
10
10
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
0
0
10
0
10
10
0
30
20
% G
% His:
10
0
10
0
0
0
0
0
0
10
0
0
0
0
20
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
0
10
20
20
0
0
10
0
20
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
10
20
0
% N
% Pro:
0
10
10
10
10
0
0
0
20
10
30
10
0
0
0
% P
% Gln:
20
10
20
10
0
10
0
10
10
0
10
10
10
10
0
% Q
% Arg:
10
10
0
10
10
10
0
10
0
20
10
0
0
0
0
% R
% Ser:
0
20
10
20
0
10
10
10
10
10
10
0
10
10
10
% S
% Thr:
10
0
0
10
0
0
10
20
0
0
0
10
20
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _