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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTOP1
All Species:
18.48
Human Site:
S194
Identified Species:
50.83
UniProt:
Q7RTM1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTM1
NP_819056.1
612
67353
S194
H
A
K
D
I
I
Q
S
F
K
T
L
E
R
F
Chimpanzee
Pan troglodytes
XP_526509
612
67423
S194
H
A
K
D
I
I
Q
S
F
K
T
L
E
R
F
Rhesus Macaque
Macaca mulatta
XP_001097009
610
67161
S194
H
A
K
D
I
I
Q
S
F
K
T
L
E
R
F
Dog
Lupus familis
XP_545943
483
53614
K104
K
H
Q
L
N
E
H
K
E
R
L
I
T
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80VM9
600
65750
S192
H
A
K
D
I
I
M
S
F
K
T
L
E
R
F
Rat
Rattus norvegicus
Q7M734
600
65910
S192
H
A
K
D
I
I
M
S
F
K
T
L
E
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515194
361
39087
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079194
408
46768
S29
P
G
M
N
Y
E
S
S
W
L
H
R
H
C
M
Zebra Danio
Brachydanio rerio
Q7ZWK8
586
65703
K188
H
I
K
D
V
I
K
K
Y
E
T
F
E
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.4
67.4
N.A.
77.6
77.2
N.A.
36.1
N.A.
21.5
41.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
95.9
71.4
N.A.
84.8
84.9
N.A.
44.4
N.A.
36.7
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
0
N.A.
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
0
N.A.
20
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
23
0
0
12
12
0
0
67
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
56
0
0
12
0
0
67
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
67
12
0
0
0
0
12
0
0
0
12
0
12
0
0
% H
% Ile:
0
12
0
0
56
67
0
0
0
0
0
12
0
0
0
% I
% Lys:
12
0
67
0
0
0
12
23
0
56
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
0
0
0
12
12
56
0
12
0
% L
% Met:
0
0
12
0
0
0
23
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
34
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
12
0
67
0
% R
% Ser:
0
0
0
0
0
0
12
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
67
0
12
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _