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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTOP3
All Species:
5.15
Human Site:
S74
Identified Species:
11.33
UniProt:
Q7RTS5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTS5
NP_839947.1
596
66296
S74
S
W
L
V
R
H
F
S
L
L
L
R
R
D
R
Chimpanzee
Pan troglodytes
XP_511667
562
62246
A64
V
Y
D
T
D
V
F
A
L
L
T
A
M
M
L
Rhesus Macaque
Macaca mulatta
XP_001097009
610
67161
L67
T
L
S
S
Q
Y
G
L
I
V
F
V
A
G
L
Dog
Lupus familis
XP_540423
578
64532
S73
Q
K
A
G
Q
L
F
S
G
L
L
A
L
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80UF9
577
64725
G68
D
R
Q
A
Q
K
A
G
Q
L
F
S
G
L
L
Rat
Rattus norvegicus
Q7M734
600
65910
G71
G
L
N
V
F
V
A
G
L
L
F
L
L
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512756
366
39394
Chicken
Gallus gallus
XP_420115
559
63424
S69
L
N
V
V
F
L
G
S
A
F
I
S
S
M
I
Frog
Xenopus laevis
NP_001079194
408
46768
Zebra Danio
Brachydanio rerio
Q7ZWK8
586
65703
S69
N
L
L
L
L
G
V
S
V
M
L
A
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394346
560
61872
R79
K
Q
R
M
M
E
E
R
S
K
S
R
R
N
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
33.4
83
N.A.
79.1
33.3
N.A.
27.1
57.8
24.5
31.2
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
100
57
49
88.2
N.A.
86
49
N.A.
37
74.3
40.9
49.1
N.A.
N.A.
38.4
N.A.
N.A.
P-Site Identity:
100
20
0
26.6
N.A.
6.6
20
N.A.
0
13.3
0
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
33.3
33.3
40
N.A.
13.3
20
N.A.
0
26.6
0
46.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
19
10
10
0
0
28
10
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
10
0
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
19
0
28
0
0
10
28
0
0
0
0
% F
% Gly:
10
0
0
10
0
10
19
19
10
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% I
% Lys:
10
10
0
0
0
10
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
28
19
10
10
19
0
10
28
46
28
10
28
10
28
% L
% Met:
0
0
0
10
10
0
0
0
0
10
0
0
10
19
0
% M
% Asn:
10
10
10
0
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
10
0
28
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
10
0
0
10
0
0
0
19
19
0
10
% R
% Ser:
10
0
10
10
0
0
0
37
10
0
10
19
10
0
0
% S
% Thr:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
10
0
10
28
0
19
10
0
10
10
0
10
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _