KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTOP2
All Species:
5.15
Human Site:
T280
Identified Species:
14.17
UniProt:
Q7RTS6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7RTS6
NP_835454.1
562
62236
T280
P
G
H
S
H
T
P
T
P
V
S
L
F
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092972
348
38575
R83
W
I
L
F
Y
L
L
R
T
V
R
C
P
C
A
Dog
Lupus familis
XP_540422
563
62118
P280
T
H
G
H
G
H
T
P
S
Q
I
S
L
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80SX5
563
62564
S281
H
G
H
G
H
T
P
S
R
V
S
L
F
R
E
Rat
Rattus norvegicus
Q7M734
600
65910
R305
R
H
Q
K
M
Q
C
R
F
D
G
V
L
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512756
366
39394
V101
F
A
A
T
L
L
Y
V
M
W
K
N
V
G
R
Chicken
Gallus gallus
XP_420115
559
63424
Y266
L
Y
P
F
N
T
E
Y
C
L
I
C
C
S
V
Frog
Xenopus laevis
NP_001079194
408
46768
K142
S
I
L
L
S
F
F
K
I
G
H
F
V
L
L
Zebra Danio
Brachydanio rerio
Q7ZWK8
586
65703
T298
S
N
R
K
R
R
S
T
G
S
T
G
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
58.1
86.6
N.A.
85
33.3
N.A.
41.4
42.7
23.6
31.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
59.9
91.3
N.A.
89.3
51.1
N.A.
48.5
60.3
40.3
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
0
N.A.
73.3
0
N.A.
0
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
0
N.A.
80
6.6
N.A.
6.6
20
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
12
0
12
0
0
23
12
12
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
23
% E
% Phe:
12
0
0
23
0
12
12
0
12
0
0
12
23
12
0
% F
% Gly:
0
23
12
12
12
0
0
0
12
12
12
12
0
12
12
% G
% His:
12
23
23
12
23
12
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
23
0
0
0
0
0
0
12
0
23
0
0
0
0
% I
% Lys:
0
0
0
23
0
0
0
12
0
0
12
0
0
0
0
% K
% Leu:
12
0
23
12
12
23
12
0
0
12
0
23
34
23
23
% L
% Met:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
12
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
12
0
12
0
0
0
23
12
12
0
0
0
12
0
0
% P
% Gln:
0
0
12
0
0
12
0
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
12
0
12
12
0
23
12
0
12
0
0
23
23
% R
% Ser:
23
0
0
12
12
0
12
12
12
12
23
12
0
12
0
% S
% Thr:
12
0
0
12
0
34
12
23
12
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
34
0
12
23
12
12
% V
% Trp:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
12
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _