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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTOP2 All Species: 15.45
Human Site: Y244 Identified Species: 42.5
UniProt: Q7RTS6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7RTS6 NP_835454.1 562 62236 Y244 Q Q G Y F Y L Y P F N I E Y S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092972 348 38575 I47 L L L A C T L I S G G A F N K
Dog Lupus familis XP_540422 563 62118 Y244 Q Q G Y F Y L Y P F N I E Y S
Cat Felis silvestris
Mouse Mus musculus Q80SX5 563 62564 Y245 Q Q G Y F Y L Y P F N I E Y S
Rat Rattus norvegicus Q7M734 600 65910 Y269 S H G I Y Y L Y P F N I E Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512756 366 39394 D65 G A G S S E G D R C T C N T T
Chicken Gallus gallus XP_420115 559 63424 E230 E S Q L R E V E Q R L A G N E
Frog Xenopus laevis NP_001079194 408 46768 R106 L Y H L L Y V R R I N Y T A R
Zebra Danio Brachydanio rerio Q7ZWK8 586 65703 Y262 S T S L Y Y L Y P F N I E Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 58.1 86.6 N.A. 85 33.3 N.A. 41.4 42.7 23.6 31.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 59.9 91.3 N.A. 89.3 51.1 N.A. 48.5 60.3 40.3 51 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 66.6 N.A. 6.6 0 13.3 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 73.3 N.A. 13.3 13.3 20 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 0 0 0 0 0 0 23 0 12 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 12 0 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 0 0 23 0 12 0 0 0 0 56 0 12 % E
% Phe: 0 0 0 0 34 0 0 0 0 56 0 0 12 0 0 % F
% Gly: 12 0 56 0 0 0 12 0 0 12 12 0 12 0 0 % G
% His: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 0 0 0 12 0 0 0 12 0 12 0 56 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 23 12 12 34 12 0 67 0 0 0 12 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 67 0 12 23 0 % N
% Pro: 0 0 0 0 0 0 0 0 56 0 0 0 0 0 0 % P
% Gln: 34 34 12 0 0 0 0 0 12 0 0 0 0 0 12 % Q
% Arg: 0 0 0 0 12 0 0 12 23 12 0 0 0 0 12 % R
% Ser: 23 12 12 12 12 0 0 0 12 0 0 0 0 0 34 % S
% Thr: 0 12 0 0 0 12 0 0 0 0 12 0 12 12 12 % T
% Val: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 34 23 67 0 56 0 0 0 12 0 56 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _